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|a Holmes, Frederic Lawrence.
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|a Meselson, Stahl, and the replication of DNA :
|b a history of "the most beautiful experiment in biology" /
|c Frederic Lawrence Holmes.
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260 |
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|a New Haven, CT :
|b Yale University Press,
|c 2001.
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|a 1 online resource (xii, 503 pages) :
|b illustrations
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|a Includes bibliographical references (pages 449-496) and index.
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|a Print version record.
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|a In 1957 Matthew Meselson and Frank Stahl produced a landmark experiment confirming that DNA replicates as predicted by the double helix structure Watson and Crick had recently proposed. It also gained immediate renown as a 'most beautiful' experiment whose beauty was tied to its simplicity. This book vividly reconstructs the complex route that led to the Meselson-Stahl experiment and provides an inside view of day-to-day scientific research - its unpredictability, excitement, intellectual challenge, and serendipitous windfalls, as well as its frustrations, unexpected diversions away from original plans, and chronic uncertainty.
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|a Contents -- Preface -- Acknowledgments -- Introduction -- The Replication Problem -- Meselson and Stahl -- Twists and Turns -- Crossing Fields: Chemical Bonds to Biological Mutants -- Dense Solutions -- The Big Machine -- Working at High Speed -- The Unseen Band -- One Discovery, Three Stories -- An Extremely Beautiful Experiment -- Centrifugal Forces -- The Subunits of Semiconservative Replication -- Images of an Experiment -- Afterword -- Abbreviations Used in Notes -- Notes -- Index
|
590 |
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|a eBooks on EBSCOhost
|b EBSCO eBook Subscription Academic Collection - Worldwide
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|a JSTOR
|b Books at JSTOR Demand Driven Acquisitions (DDA)
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|a ProQuest Ebook Central
|b Ebook Central Academic Complete
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600 |
1 |
0 |
|a Meselson, Matthew.
|
600 |
1 |
0 |
|a Stahl, Franklin W.
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600 |
1 |
7 |
|a Meselson, Matthew
|2 fast
|1 https://id.oclc.org/worldcat/entity/E39PBJfGWyVfphGkg6fhPkvmBP
|
600 |
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7 |
|a Stahl, Franklin W.
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|1 https://id.oclc.org/worldcat/entity/E39PBJrgGT9X3GJX6jC9wWPbBP
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600 |
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|a Meselson, Matthew Stanley
|d 1930-
|2 gnd
|
600 |
1 |
7 |
|a Stahl, Franklin William
|d 1929-
|2 gnd
|
600 |
1 |
7 |
|a Meselson, Matthew Stanley.
|2 swd
|
600 |
1 |
7 |
|a Stahl, Franklin William.
|2 swd
|
650 |
|
0 |
|a DNA replication
|x Experiments
|x History.
|
650 |
|
0 |
|a Molecular biology
|x Experiments
|x History.
|
650 |
|
0 |
|a DNA replication.
|
650 |
|
2 |
|a DNA Replication
|
650 |
|
2 |
|a Molecular Biology
|x history
|
650 |
|
6 |
|a ADN
|x Réplication
|x Expériences
|x Histoire.
|
650 |
|
6 |
|a Biologie moléculaire
|x Expériences
|x Histoire.
|
650 |
|
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|a ADN
|x Réplication.
|
650 |
|
7 |
|a SCIENCE
|x Life Sciences
|x Genetics & Genomics.
|2 bisacsh
|
650 |
|
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|a SCIENCE
|x History.
|2 bisacsh
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650 |
|
7 |
|a DNA replication
|2 fast
|
650 |
|
7 |
|a Molecular biology
|x Experiments
|2 fast
|
650 |
|
7 |
|a Replikation
|2 gnd
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650 |
|
7 |
|a Meselson-Stahl-Experiment
|2 gnd
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650 |
1 |
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|a DNA.
|2 gtt
|
650 |
1 |
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|a Replicatie (biochemie)
|2 gtt
|
655 |
|
7 |
|a History
|2 fast
|
758 |
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|i has work:
|a Meselson, Stahl, and the replication of DNA (Text)
|1 https://id.oclc.org/worldcat/entity/E39PCGFRXx39tWQyD4mFDtRKr3
|4 https://id.oclc.org/worldcat/ontology/hasWork
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776 |
0 |
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|i Print version:
|a Holmes, Frederic Lawrence.
|t Meselson, Stahl, and the replication of DNA.
|d New Haven, CT : Yale University Press, 2001
|w (DLC) 2001017701
|
856 |
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