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The art of drug synthesis /
The Art of Drug Synthesis illustrates how chemistry, biology, pharmacokinetics, and a host of other disciplines come together to produce successful medicines. The authors have compiled a collection of 21 representative categories of drugs, from which they have selected as examples many of the best-s...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Hoboken, N.J. :
Wiley-Interscience,
[2007]
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| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 245 | 0 | 4 | |a The art of drug synthesis / |c edited by Douglas S. Johnson, Jie Jack Li, Pfizer Global Research and Development |
| 264 | 1 | |a Hoboken, N.J. : |b Wiley-Interscience, |c [2007] | |
| 264 | 4 | |c ©2007 | |
| 300 | |a 1 online resource (xv, 276 pages) : |b illustrations | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
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| 347 | |a data file | ||
| 520 | |a The Art of Drug Synthesis illustrates how chemistry, biology, pharmacokinetics, and a host of other disciplines come together to produce successful medicines. The authors have compiled a collection of 21 representative categories of drugs, from which they have selected as examples many of the best-selling drugs on the market today. An introduction to each drug is provided, as well as background to the biology, pharmacology, pharmacokinetics, and drug metabolism, followed by a detailed account of the drug synthesis.:.; Edited by prominent scientists working in drug discovery for Pfizer.; Meets. | ||
| 504 | |a Includes bibliographical references and index. | ||
| 505 | 0 | |a The role of medicinal chemistry in drug discovery / John A. Lowe III -- Process research: how much? how soon? / Neal G. Anderson -- Aromatase inhibitors for breast cancer : exemestane (Aromasin), anastrozole (Arimidex), and letrozole (Femara) / Jie Jack Li -- Quinolone antibiotics : levofloxacin (Levaquin), moxifloxacin (Avelox), gemifloxacin (Factive), and garenoxacin (T-3811) / Chris Limberakis -- Triazole antifungals : itraconazole (Sporanox), fluconazole (Diflucan), voriconazole (Vfend), and fosfluconazole (Prodif) / Andrew S. Bell -- Non-nucleoside HIV reverse transcriptase inhibitors / Arthur Harms -- Neuraminidase inhibitors for influenza : oseltamivir phosphate (Tamiflu) and zanamivir (Relenza) / Douglas S. Johnson and Jie Jack Li -- Peroxisome proliferator-activated receptor (PPAR) agonists for type 2 diabetes / Jin Li -- Angiotensin AT1 antagonists for hypertension / Larry Yet -- Leading ACE inhibitors for hypertension / Victor J. Cee and Edward J. Olhava -- Dihydropyridine calcium channel blockers for hypertension / Daniel P. Christen -- Second-generation HMG-CoA reductase inhibitors / Jeffrey A. Pfefferkorn -- Cholesterol absorption inhibitors: ezetimibe (zetia) / Stuart B. Rosenblum -- Dual selective serotonin and norepinephrine reuptake inhibitors (SSNRIs) for depression / Marta Piñeiro-Núñez -- GABA receptor agonists for insomnia : zolpidem (Ambien), zaleplon (Sonata), eszopiclone (Estorra, Lunesta), and indiplon / Peter R. Guzzo -- Ligands: neurontin (Gabapentin) and lyrica (Pregabalin) / Po-Wai Yuen -- Approved treatments for attention deficit hyperactivity disorder : amphetamine (Adderall), methylphenidate (Ritalin), and atomoxetine (Straterra) / David L. Gray. | |
| 546 | |a English. | ||
| 588 | 0 | |a Print version record | |
| 590 | |a ProQuest Ebook Central |b Ebook Central Academic Complete | ||
| 650 | 0 | |a Drugs |x Design. | |
| 650 | 0 | |a Pharmaceutical chemistry. | |
| 650 | 2 | |a Drug Design | |
| 650 | 2 | |a Chemistry, Pharmaceutical |x methods | |
| 650 | 2 | |a Chemistry, Pharmaceutical | |
| 650 | 6 | |a Médicaments |x Conception. | |
| 650 | 6 | |a Chimie pharmaceutique. | |
| 650 | 7 | |a MEDICAL |x Drug Guides. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Pharmacology. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Pharmacy. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Nursing |x Pharmacology. |2 bisacsh | |
| 650 | 7 | |a Drugs |x Design |2 fast | |
| 650 | 7 | |a Pharmaceutical chemistry |2 fast | |
| 700 | 1 | |a Johnson, Douglas S. |q (Douglas Scott), |d 1968- |1 https://id.oclc.org/worldcat/entity/E39PCjJ8FC6TJpcbMyytwr96jC | |
| 700 | 1 | |a Li, Jie Jack. | |
| 758 | |i has work: |a The art of drug synthesis (Text) |1 https://id.oclc.org/worldcat/entity/E39PCGRYCgkyqgrqCkBTfdChHC |4 https://id.oclc.org/worldcat/ontology/hasWork | ||
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