Cell Line Development

Mammalian cell lines command an effective monopoly for the production of therapeutic proteins that require post-translational modifications. This unique advantage outweighs the costs associated with mammalian cell culture, which are far grater in terms of development time and manufacturing when comp...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Al-Rubeai, Mohamed (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Dordrecht : Springer Netherlands : Imprint: Springer, 2009.
Edición:1st ed. 2009.
Colección:Cell Engineering ; 6
Temas:
Medicine > Research.
Biology > Research.
Cytology.
Biotechnology.
Biochemistry.
Biomedical Research.
Cell Biology.
Chemical Bioengineering.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Use of MAR Elements to Increase the Production of Recombinant Proteins
  • Expression Engineering - The IE2 Promoter/Enhancer from Mouse CMV
  • Defeating Randomness - Targeted Integration as a Boost for Biotechnology
  • Importance of Genetic Environment for Recombinant Gene Expression
  • Expression Vector Engineering for Recombinant Protein Production
  • Cell Xpress™ Applications in Development and Characterization of Biopharmaceutical Recombinant Protein Producing Cell Lines
  • Selection Methods for High-Producing Mammalian Cell Lines
  • Engineering Mammalian Cells for Recombinant Monoclonal Antibody Production
  • Engineering Cell Function by RNA Interference
  • Apoptosis and Autophagy Cell Engineering
  • Glycoengineering and Modeling of Protein N-Glycosylation
  • Engineering the Secretory Pathway in Mammalian Cells.

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