Entry Inhibitors in HIV Therapy

Entry Inhibitors in HIV Therapy presents the current status of this relatively new and highly dynamic class of inhibitors and provides a unique overview of obstacles and considerations for HIV entry inhibition compared to other antiretroviral targets. The introductory chapters of this book present a...

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Bibliographic Details
Call Number:Libro Electrónico
Corporate Author: SpringerLink (Online service)
Other Authors: Reeves, Jacqueline D. (Editor), Derdeyn, Cynthia A. (Editor)
Format: Electronic eBook
Language:Inglés
Published: Basel : Birkhäuser Basel : Imprint: Birkhäuser, 2007.
Edition:1st ed. 2007.
Series:Milestones in Drug Therapy,
Subjects:
Pharmacology.
Immunology.
Virology.
Diseases.
Pathology.
Cytology.
Cell Biology.
Online Access:Texto Completo
Table of Contents:
  • to entry inhibitors in the management of HIV infection
  • The challenge of HIV sequence diversity in the envelope glycoprotein
  • Attachment of human immunodeficiency virus to cells and its inhibition
  • Inhibitors that target gp120-CD4 interactions
  • Inhibitors that target gp120 interactions with coreceptor
  • Inhibitors that target fusion
  • HIV-1 entry inhibitors as microbicides
  • Entry inhibition of HIV-1 subtype C isolates
  • The utility of coreceptor typing in the clinic
  • Future clinical prospects for entry inhibitors
  • Enfuvirtide: from basic science to FDA approval
  • Targets for drug development - past and present.

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