Erythropoietins and Erythropoiesis Molecular, Cellular, Preclinical, and Clinical Biology /

Research on, and interest in, red blood cell formation spans several centuries and was thought to have peaked in the 1980s with the cloning of the eryth- poietin (EPO) gene. In the years subsequent to the cloning of EPO and its expression as a recombinant protein, much was written about EPO. Althoug...

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Bibliographic Details
Call Number:Libro Electrónico
Corporate Author: SpringerLink (Online service)
Other Authors: Molineux, Graham (Editor), Foote, Mary A. (Editor), Elliott, Steven (Editor)
Format: Electronic eBook
Language:Inglés
Published: Basel : Birkhäuser Basel : Imprint: Birkhäuser, 2006.
Edition:1st ed. 2006.
Series:Milestones in Drug Therapy,
Subjects:
Pharmacology.
Cytology.
Sports medicine.
Endocrinology.
Cell Biology.
Sports Medicine.
Online Access:Texto Completo
Table of Contents:
  • Background and basic science
  • Erythropoiesis: an overview
  • Studies of erythropoiesis and the discovery and cloning of recombinant human erythropoietin
  • Structural basis for the signal transduction of erythropoietin
  • Molecular biology of the erythropoietin receptor in hematopoietic and non-hematopoietic tissues
  • Erythropoietin receptor signaling processes
  • Clinical pharmacokinetic properties of rHuEPO: a review
  • Biology of erythropoietin
  • Commercial production of recombinant erythropoietins
  • Clinical use of recombinant erythropoietins
  • Use of recombinant erythropoietins in the setting of renal disease
  • Erythropoietic therapy in the practice of oncology
  • Use of recombinant erythropoietins for the treatment of anemia of chronic disease
  • Use of erythropoietins in the surgical setting
  • Abuse of recombinant erythropoietins by athletes
  • Antibodies to endogenous and recombinant erythropoietin
  • New molecules and formulations of recombinant human erythropoietin.

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