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Complement and Kidney Disease
It is evident that a defective or deregulated complement system results in kidney diseases. An important role of complement effector and regulatory proteins in pathological settings of the kidney has been demonstrated. A large panel of distinct human kidney diseases is caused by defective complement...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor Corporativo: | |
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Basel :
Birkhäuser Basel : Imprint: Birkhäuser,
2006.
|
| Edición: | 1st ed. 2006. |
| Colección: | Progress in Inflammation Research,
|
| Temas: | |
| Acceso en línea: | Texto Completo |
MARC
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|---|---|---|---|
| 001 | 978-3-7643-7428-0 | ||
| 003 | DE-He213 | ||
| 005 | 20220111132135.0 | ||
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| 008 | 100301s2006 sz | s |||| 0|eng d | ||
| 020 | |a 9783764374280 |9 978-3-7643-7428-0 | ||
| 024 | 7 | |a 10.1007/3-7643-7428-4 |2 doi | |
| 050 | 4 | |a QR180-189.5 | |
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| 245 | 1 | 0 | |a Complement and Kidney Disease |h [electronic resource] / |c edited by Peter F Zipfel. |
| 250 | |a 1st ed. 2006. | ||
| 264 | 1 | |a Basel : |b Birkhäuser Basel : |b Imprint: Birkhäuser, |c 2006. | |
| 300 | |a XVI, 236 p. |b online resource. | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 347 | |a text file |b PDF |2 rda | ||
| 490 | 1 | |a Progress in Inflammation Research, |x 2296-4525 | |
| 505 | 0 | |a The complement system in renal diseases -- Complement in renal transplantation -- C1q and the glomerulonephritides: therapeutic approaches for the treatment of complement-mediated kidney diseases -- Complement deficient mice as model systems for kidney diseases -- Non-Shiga toxin-associated hemolytic uremic syndrome -- Role of complement and Factor H in hemolytic uremic syndrome -- Genetic testing in atypical HUS and the role of membrane cofactor protein (MCP; CD46) and Factor I -- Towards a new classification of hemolytic uremic syndrome -- Therapeutic strategies for atypical and recurrent hemolytic uremic syndromes (HUS) -- Complement defects in children which result in kidney diseases: diagnosis and therapy -- The role of complement in membranoproliferative glomerulonephritis -- The experience of a patient advocacy group. | |
| 520 | |a It is evident that a defective or deregulated complement system results in kidney diseases. An important role of complement effector and regulatory proteins in pathological settings of the kidney has been demonstrated. A large panel of distinct human kidney diseases is caused by defective complement control. Genetic analyses have identified mutations in complement regulators that are associated with these diseases. Mutations have been identified in the fluid phase alternative pathway regulator Factor H and the membrane regulator Membrane Cofactor Protein MCP (CD46). The functional characterization of the mutant proteins allows to define the pathophysiological events on a molecular level. These new concepts and data on disease mechanisms allowed establishing new diagnostic and promising therapeutic approaches for several human kidney diseases. Molecular biology, clinics and therapy are discussed in this volume. | ||
| 650 | 0 | |a Immunology. | |
| 650 | 0 | |a Cytology. | |
| 650 | 0 | |a Nephrology. | |
| 650 | 0 | |a Human physiology. | |
| 650 | 0 | |a Internal medicine. | |
| 650 | 0 | |a Medical microbiology. | |
| 650 | 1 | 4 | |a Immunology. |
| 650 | 2 | 4 | |a Cell Biology. |
| 650 | 2 | 4 | |a Nephrology. |
| 650 | 2 | 4 | |a Human Physiology. |
| 650 | 2 | 4 | |a Internal Medicine. |
| 650 | 2 | 4 | |a Medical Microbiology. |
| 700 | 1 | |a Zipfel, Peter F. |e editor. |4 edt |4 http://id.loc.gov/vocabulary/relators/edt | |
| 710 | 2 | |a SpringerLink (Online service) | |
| 773 | 0 | |t Springer Nature eBook | |
| 776 | 0 | 8 | |i Printed edition: |z 9783764390440 |
| 776 | 0 | 8 | |i Printed edition: |z 9783764371661 |
| 830 | 0 | |a Progress in Inflammation Research, |x 2296-4525 | |
| 856 | 4 | 0 | |u https://doi.uam.elogim.com/10.1007/3-7643-7428-4 |z Texto Completo |
| 912 | |a ZDB-2-SBL | ||
| 912 | |a ZDB-2-SXB | ||
| 950 | |a Biomedical and Life Sciences (SpringerNature-11642) | ||
| 950 | |a Biomedical and Life Sciences (R0) (SpringerNature-43708) | ||