Sialo-Xenoantigenic Glycobiology Molecular Glycobiology of Sialylglycan-Xenoantigenic Determinants in Pig to Human Xenotransplantation /

Carbohydrate antigens on glycoconjugates of mammalian cells play crucial roles in various biological processes and are epitopes recognized by the immune system, as glycobiology has hugely been progressed during the past two decades. The book focuses on sialic acid-based xenoantigenes. In pig to huma...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autores principales: Song, Kwon-Ho (Autor), Kim, Cheorl-Ho (Autor)
Autor Corporativo: SpringerLink (Online service)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2013.
Edición:1st ed. 2013.
Colección:Sungkyunkwan University Outstanding Research, 1
Temas:
Biomedical engineering.
Medicine-Research.
Biology-Research.
Medical genetics.
Clinical biochemistry.
Biochemistry.
Biomedical Engineering and Bioengineering.
Biomedical Research.
Medical Genetics.
Medical Biochemistry.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Screening of pig glycosyltransferase genes related to xenoantigens and their masking
  • Cloning and tissue specific expression of pcmah and its alternative transcripts
  • Functional characterization of pCMAH in the synthesis of N-glycolylneuraminic acid as the xenoantigenic determinant in pig-to-human xenotransplantation
  • Identification of two alternative promoters of the pig CMP-N-acetylneuraminic acid hydroxylase gene
  • Screening for xenoantigenic determinants formed by sialyltransferases.

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