Cargando…
Numerical Methods for the Life Scientist Binding and Enzyme Kinetics Calculated with GNU Octave and MATLAB /
Enzyme kinetics, binding kinetics and pharmacological dose-response curves are currently analyzed by a few standard methods. Some of these, like Michaelis-Menten enzyme kinetics, use plausible approximations, others, like Hill equations for dose-response curves, are outdated. Calculating realistic r...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor principal: | |
| Autor Corporativo: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Berlin, Heidelberg :
Springer Berlin Heidelberg : Imprint: Springer,
2011.
|
| Edición: | 1st ed. 2011. |
| Temas: | |
| Acceso en línea: | Texto Completo |
MARC
| LEADER | 00000nam a22000005i 4500 | ||
|---|---|---|---|
| 001 | 978-3-642-20820-1 | ||
| 003 | DE-He213 | ||
| 005 | 20220203105538.0 | ||
| 007 | cr nn 008mamaa | ||
| 008 | 110804s2011 gw | s |||| 0|eng d | ||
| 020 | |a 9783642208201 |9 978-3-642-20820-1 | ||
| 024 | 7 | |a 10.1007/978-3-642-20820-1 |2 doi | |
| 050 | 4 | |a QH324.2-324.25 | |
| 072 | 7 | |a UY |2 bicssc | |
| 072 | 7 | |a PS |2 bicssc | |
| 072 | 7 | |a SCI056000 |2 bisacsh | |
| 072 | 7 | |a PSAX |2 thema | |
| 082 | 0 | 4 | |a 570.285 |2 23 |
| 100 | 1 | |a Prinz, Heino. |e author. |4 aut |4 http://id.loc.gov/vocabulary/relators/aut | |
| 245 | 1 | 0 | |a Numerical Methods for the Life Scientist |h [electronic resource] : |b Binding and Enzyme Kinetics Calculated with GNU Octave and MATLAB / |c by Heino Prinz. |
| 250 | |a 1st ed. 2011. | ||
| 264 | 1 | |a Berlin, Heidelberg : |b Springer Berlin Heidelberg : |b Imprint: Springer, |c 2011. | |
| 300 | |a IX, 149 p. 61 illus., 52 illus. in color. |b online resource. | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 347 | |a text file |b PDF |2 rda | ||
| 505 | 0 | |a Preparing the computer -- Binding equilibria -- Binding kinetics -- Least squares fit to experimental data -- Multi-parameter fits -- Comparing the two different approaches. . | |
| 520 | |a Enzyme kinetics, binding kinetics and pharmacological dose-response curves are currently analyzed by a few standard methods. Some of these, like Michaelis-Menten enzyme kinetics, use plausible approximations, others, like Hill equations for dose-response curves, are outdated. Calculating realistic reaction schemes requires numerical mathematical routines which usually are not covered in the curricula of life science. This textbook will give a step-by-step introduction to numerical solutions of non-linear and differential equations. It will be accompanied with a set of programs to calculate any reaction scheme on any personal computer. Typical examples from analytical biochemistry and pharmacology can be used as versatile templates. When a reaction scheme is applied for data fitting, the resulting parameters may not be unique. Correlation of parameters will be discussed and simplification strategies will be offered. | ||
| 650 | 0 | |a Bioinformatics. | |
| 650 | 0 | |a Biomathematics. | |
| 650 | 1 | 4 | |a Bioinformatics. |
| 650 | 2 | 4 | |a Computational and Systems Biology. |
| 650 | 2 | 4 | |a Mathematical and Computational Biology. |
| 710 | 2 | |a SpringerLink (Online service) | |
| 773 | 0 | |t Springer Nature eBook | |
| 776 | 0 | 8 | |i Printed edition: |z 9783642208195 |
| 776 | 0 | 8 | |i Printed edition: |z 9783642208218 |
| 776 | 0 | 8 | |i Printed edition: |z 9783662505878 |
| 856 | 4 | 0 | |u https://doi.uam.elogim.com/10.1007/978-3-642-20820-1 |z Texto Completo |
| 912 | |a ZDB-2-SBL | ||
| 912 | |a ZDB-2-SXB | ||
| 950 | |a Biomedical and Life Sciences (SpringerNature-11642) | ||
| 950 | |a Biomedical and Life Sciences (R0) (SpringerNature-43708) | ||