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Ion Channels and Their Inhibitors
Being the crucial components of living cells, ion channels are important targets of therapeutic agents. Historically, it has been challenging to develop drugs on this target class. A major issue with target based ion channel drug development is the identification of effective small chemical leads fo...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor Corporativo: | |
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Berlin, Heidelberg :
Springer Berlin Heidelberg : Imprint: Springer,
2011.
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| Edición: | 1st ed. 2011. |
| Temas: | |
| Acceso en línea: | Texto Completo |
MARC
| LEADER | 00000nam a22000005i 4500 | ||
|---|---|---|---|
| 001 | 978-3-642-19922-6 | ||
| 003 | DE-He213 | ||
| 005 | 20220116160747.0 | ||
| 007 | cr nn 008mamaa | ||
| 008 | 110621s2011 gw | s |||| 0|eng d | ||
| 020 | |a 9783642199226 |9 978-3-642-19922-6 | ||
| 024 | 7 | |a 10.1007/978-3-642-19922-6 |2 doi | |
| 050 | 4 | |a RS400-431 | |
| 072 | 7 | |a PNN |2 bicssc | |
| 072 | 7 | |a PSB |2 bicssc | |
| 072 | 7 | |a SCI013020 |2 bisacsh | |
| 072 | 7 | |a PNB |2 thema | |
| 082 | 0 | 4 | |a 615.19 |2 23 |
| 245 | 1 | 0 | |a Ion Channels and Their Inhibitors |h [electronic resource] / |c edited by Satya Prakash Gupta. |
| 250 | |a 1st ed. 2011. | ||
| 264 | 1 | |a Berlin, Heidelberg : |b Springer Berlin Heidelberg : |b Imprint: Springer, |c 2011. | |
| 300 | |a XIII, 348 p. |b online resource. | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 347 | |a text file |b PDF |2 rda | ||
| 505 | 0 | |a Structural and Functional Discrimination of Membrane -- Proteins -- Pharmacology of Hyperpolarization-Activated Cyclic Nucleotide-Gated (HCN) Channels -- Advanced Molecular Modeling Techniques Applied to Ion Channels Blockers -- Advances in Design and Development of Sodium Channel Blockers -- Potassium Channel Blockers as Anti-arrhythmic Agents.- hERG Potassium Channels in Drug Discovery and Development -- Prediction of hERG Channel Inhibition Using in silico Techniques -- Advances in Structure-Activity Relationship Studies on Potassium Channel Modulators -- Calcium Ion Channels and Their Blockers -- Therapeutic Potential of N-type Voltage Gated Ca2+ Channel -- Chloride Ion Channels: Structure, Functions, and Blockers. | |
| 520 | |a Being the crucial components of living cells, ion channels are important targets of therapeutic agents. Historically, it has been challenging to develop drugs on this target class. A major issue with target based ion channel drug development is the identification of effective small chemical leads for medicinal chemistry optimization to the clinical candidate status. Thus enough attention has been paid to the study of structure and functions of ion channels and their potential inhibitors. The present book compiles important chapters authored by eminent workers in the field to cover important recent advances in the studies of the structure and functions of ion channels and their inhibitors, such as sodium ion, potassium ion, chloride ion, calcium ion channel inhibitors. The book may be of great use to the students and scientists working in the area of molecular biology, biochemistry, physiology, neurobiology, and medicinal chemistry. | ||
| 650 | 0 | |a Medicinal chemistry. | |
| 650 | 0 | |a Medicine-Research. | |
| 650 | 0 | |a Biology-Research. | |
| 650 | 0 | |a Proteins . | |
| 650 | 0 | |a Pharmacy. | |
| 650 | 1 | 4 | |a Medicinal Chemistry. |
| 650 | 2 | 4 | |a Biomedical Research. |
| 650 | 2 | 4 | |a Protein Biochemistry. |
| 650 | 2 | 4 | |a Pharmacy. |
| 700 | 1 | |a Gupta, Satya Prakash. |e editor. |4 edt |4 http://id.loc.gov/vocabulary/relators/edt | |
| 710 | 2 | |a SpringerLink (Online service) | |
| 773 | 0 | |t Springer Nature eBook | |
| 776 | 0 | 8 | |i Printed edition: |z 9783642442827 |
| 776 | 0 | 8 | |i Printed edition: |z 9783642199233 |
| 776 | 0 | 8 | |i Printed edition: |z 9783642199219 |
| 856 | 4 | 0 | |u https://doi.uam.elogim.com/10.1007/978-3-642-19922-6 |z Texto Completo |
| 912 | |a ZDB-2-CMS | ||
| 912 | |a ZDB-2-SXC | ||
| 950 | |a Chemistry and Materials Science (SpringerNature-11644) | ||
| 950 | |a Chemistry and Material Science (R0) (SpringerNature-43709) | ||