Small Molecules in Oncology

Show other versions (1)

Extensive research into the molecular mechanisms of cancer disease has heralded a new age of targeted therapy. In malignant cells, key proteins that are crucial to tumor growth and survival are now being targeted directly with rationally designed inhibitors. Apart from monoclonal antibodies, small m...

Full description

Bibliographic Details
Call Number:Libro Electrónico
Corporate Author: SpringerLink (Online service)
Other Authors: Martens, Uwe M. (Editor)
Format: Electronic eBook
Language:Inglés
Published: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2010.
Edition:1st ed. 2010.
Series:Recent Results in Cancer Research, 184
Subjects:
Oncology.
Hematology.
Cancer.
Cancer Biology.
Online Access:Texto Completo
Table of Contents:
  • Protein kinase inhibitors
  • Imatinib Mesylate
  • Erlotinib
  • Axitinib (AG-013736)
  • Lapatinib
  • Sorafenib
  • Sunitinib
  • Dasatinib
  • Nilotinib
  • Bosutinib
  • Epigenetic modifiers
  • Decitabine
  • 5-Azacytidine/Azacitidine
  • Cell cycle inhibitors
  • Bortezomib
  • Temsirolimus
  • Danusertib (formerly PHA-739358) - A Novel Combined Pan-Aurora Kinases and Third Generation Bcr-Abl Tyrosine Kinase Inhibitor
  • BI_2536 - Targeting the Mitotic Kinase Polo-Like Kinase 1 (Plk1)
  • Other novel agents
  • Imetelstat (GRN163L) - Telomerase-Based Cancer Therapy
  • GDC-0449 - Targeting the Hedgehog Signaling Pathway.

Similar Items