Sparking Signals Kinases as Molecular Signaltransducers and Pharmacological Drug Targets in Inflammation /

Protein phosphorylation is an essential post-translational modification that modulates cell-cell communication. Substrate phosphorylation by protein kinases controls intracellular signal transduction pathways that mediate cell proliferation, migration, differentiation, and metabolism. The importance...

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Bibliographic Details
Call Number:Libro Electrónico
Corporate Author: SpringerLink (Online service)
Other Authors: Baier, Gottfried (Editor), Schraven, Burkhart (Editor), Zügel, Ulrich (Editor), Bonin, Arne (Editor)
Format: Electronic eBook
Language:Inglés
Published: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2008.
Edition:1st ed. 2008.
Series:Ernst Schering Foundation Symposium Proceedings ; 2007/3
Subjects:
Pharmacology.
Immunology.
Biochemistry.
Online Access:Texto Completo
Table of Contents:
  • Proteomics-Based Strategies in Kinase Drug Discovery
  • PKC Isotype Functions in T Lymphocytes
  • Migration, Cell-Cell Interaction and Adhesion in the Immune System
  • Molecular Mechanisms that Control Leukocyte Extravasation Through Endothelial Cell Contacts
  • Fragment-Based Drug Discovery Using Rational Design
  • Systems Biology of T Cell Activation
  • Solving the IRAK-4 Enigma: Application of Kinase-Dead Knock-In Mice
  • Sensing, Presenting, and Regulating PAMPS
  • The Role of Diacylglycerol Kinases in T Cell Anergy.

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