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Insights into Receptor Function and New Drug Development Targets
G-Protein Coupled receptors (GPCRs) and other receptors are significant targets for drug discovery, due to their roles in fundamental physiological processes. Among these roles are: regulation of growth, food intake, reproduction, water balance, sensory perception, blood pressure and heart rate. GPC...
| Call Number: | Libro Electrónico |
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| Corporate Author: | |
| Other Authors: | , |
| Format: | Electronic eBook |
| Language: | Inglés |
| Published: |
Berlin, Heidelberg :
Springer Berlin Heidelberg : Imprint: Springer,
2006.
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| Edition: | 1st ed. 2006. |
| Series: | Research and Perspectives in Endocrine Interactions,
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| Subjects: | |
| Online Access: | Texto Completo |
Table of Contents:
- Molecular and functional diversity of the TRPC family of ion channels. TRPC channels and their role in ROCE/SOCE
- Functional Rescue of Misfolded Receptor Mutants
- Obesity-related mutations of leptin and melanocortin receptors
- cAMP- and cGMP-dependent control of lipolysis and lipid mobilization in humans: putative targets for fat cell management
- Central Neuropeptide Receptors Involved in Water Balance: Application to Apelin
- Targeting regulators of G protein signaling (RGS proteins) to enhance agonist specificity
- Dimeric GPCRs: what did we learn from the metabotropic glutamate receptors?
- Guiding principles applied in the design of GPCR-selective hypothalamic hormone agonists and antagonists
- Mutations in G proteins and G protein-coupled receptors in human endocrine diseases
- A molecular dissection of the glycoprotein hormone receptors
- Receptor Tyrosine Kinases as Targets for Cancer Therapy Development
- Targets for pituitary tumor therapy
- The endogenous cannabinoid system in the control of food intake and energy balance.