Simple Mathematical Models of Gene Regulatory Dynamics

This is a short and self-contained introduction to the field of mathematical modeling of gene-networks in bacteria. As an entry point to the field, we focus on the analysis of simple gene-network dynamics. The notes commence with an introduction to the deterministic modeling of gene-networks, with e...

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Bibliographic Details
Call Number:Libro Electrónico
Main Authors: Mackey, Michael C. (Author), Santillán, Moisés (Author), Tyran-Kamińska, Marta (Author), Zeron, Eduardo S. (Author)
Corporate Author: SpringerLink (Online service)
Format: Electronic eBook
Language:Inglés
Published: Cham : Springer International Publishing : Imprint: Springer, 2016.
Edition:1st ed. 2016.
Series:Lecture Notes on Mathematical Modelling in the Life Sciences,
Subjects:
Molecular genetics.
Biomathematics.
Bioinformatics.
Mathematics.
Differential equations.
Probabilities.
Molecular Genetics.
Mathematical and Computational Biology.
Computational and Systems Biology.
Applications of Mathematics.
Differential Equations.
Probability Theory.
Online Access:Texto Completo
Table of Contents:
  • Introduction
  • Part I Deterministic Modeling Techniques
  • 1.Generic deterministic models of prokaryotic gene regulation
  • 2.General dynamic considerations
  • Part II Dealing with Noise
  • 3.Master equation modeling approaches
  • 4.Noise effects in gene regulation: Intrinsic versus extrinsic
  • Part III Specific Examples
  • 5.The lactose operon
  • 6.The tryptophan operon
  • 7.The Lysis-Lysogeny Switch
  • Index
  • References.

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