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Mitochondrial Mechanisms of Degeneration and Repair in Parkinson's Disease

This volume brings together various theories of how aberrations in mitochondrial function and morphology contribute to neurodegeneration in idiopathic and familial forms of Parkinson's disease. Moreover, it comprehensively reviews the current search for therapies, and proposes how molecules are...

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Bibliographic Details
Call Number:Libro Electrónico
Corporate Author: SpringerLink (Online service)
Other Authors: Buhlman, Lori M. (Editor)
Format: Electronic eBook
Language:Inglés
Published: Cham : Springer International Publishing : Imprint: Springer, 2016.
Edition:1st ed. 2016.
Subjects:
Online Access:Texto Completo
Table of Contents:
  • Mitochondrial ROS and Apoptosis
  • Dopamine Metabolism and Reactive Oxygen Species Production
  • The Consequences of Damaged Mitochondrial DNA
  • The role of chronic inflammation in the etiology of Parkinson's disease
  • Ion-Catalyzed Reactive Oxygen Species in Sporadic Models of Parkinson's Disease
  • Toxin Mediated Complex I Inhibition and Parkinson's Disease
  • Parkinson Disease-Associated Mutations Affect Mitochondrial Function
  • PARKIN/PINK1 Pathway for the Selective Isolation and Degradation of Impaired Mitochondria
  • Mitochondrial Therapeutic approaches in Parkinson's Disease
  • Altering Mitochondrial Fusion and Fission Protein Levels Rescues Parkin and PINK1 Loss-of-Function Phenotypes
  • Early Nicotine Exposure is Protective in Familial and Idiopathic Models of Parkinson's Disease
  • Transcription Modulation of Mitochondrial Function and Related Pathways as a Therapeutic Opportunity in Parkinson's Disease
  • Delivery of Biologically Active Molecules to Mitochondria.