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Dynamics of Cell Fate Decision Mediated by the Interplay of Autophagy and Apoptosis in Cancer Cells Mathematical Modeling and Experimental Observations /

This interdisciplinary thesis introduces a systems biology approach to study the cell fate decision mediated by autophagy. A mathematical model of interaction between Autophagy and Apoptosis in mammalian cells is proposed. In this dynamic model autophagy acts as a gradual response to stress (Rheosta...

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Détails bibliographiques
Cote:Libro Electrónico
Auteur principal: Tavassoly, Iman (Auteur)
Collectivité auteur: SpringerLink (Online service)
Format: Électronique eBook
Langue:Inglés
Publié: Cham : Springer International Publishing : Imprint: Springer, 2015.
Édition:1st ed. 2015.
Collection:Springer Theses, Recognizing Outstanding Ph.D. Research,
Sujets:
Accès en ligne:Texto Completo
Table des matières:
  • Introduction
  • Mathematical Modeling of the Interplay of Autophagy and Apoptosis
  • An Experimental Framework to Study the Dynamics of Autophagic Response
  • Conclusions
  • Source Code.