Dynamics of Cell Fate Decision Mediated by the Interplay of Autophagy and Apoptosis in Cancer Cells Mathematical Modeling and Experimental Observations /

This interdisciplinary thesis introduces a systems biology approach to study the cell fate decision mediated by autophagy. A mathematical model of interaction between Autophagy and Apoptosis in mammalian cells is proposed. In this dynamic model autophagy acts as a gradual response to stress (Rheosta...

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Bibliographic Details
Call Number:Libro Electrónico
Main Author: Tavassoly, Iman (Author)
Corporate Author: SpringerLink (Online service)
Format: Electronic eBook
Language:Inglés
Published: Cham : Springer International Publishing : Imprint: Springer, 2015.
Edition:1st ed. 2015.
Series:Springer Theses, Recognizing Outstanding Ph.D. Research,
Subjects:
Biomaterials.
Bioinformatics.
Cancer.
Cytology.
Biophysics.
Computational and Systems Biology.
Cancer Biology.
Cell Biology.
Online Access:Texto Completo
Table of Contents:
  • Introduction
  • Mathematical Modeling of the Interplay of Autophagy and Apoptosis
  • An Experimental Framework to Study the Dynamics of Autophagic Response
  • Conclusions
  • Source Code.

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