Mechanisms of Atrial Arrhythmias Insights from the Development of a Biophysically Detailed Model of the Human Atria /

This thesis describes the development of biophysically detailed computer models of the human atria and torso to study the underlying mechanisms of cardiac diseases, some of the most common causes of morbidity and mortality. This is a cross-disciplinary project, involving fundamentals of cardiac elec...

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Bibliographic Details
Call Number:Libro Electrónico
Main Author: Colman, Michael A. (Author)
Corporate Author: SpringerLink (Online service)
Format: Electronic eBook
Language:Inglés
Published: Cham : Springer International Publishing : Imprint: Springer, 2014.
Edition:1st ed. 2014.
Series:Springer Theses, Recognizing Outstanding Ph.D. Research,
Subjects:
Biophysics.
Cardiology.
Bioinformatics.
Mathematical physics.
Computational and Systems Biology.
Theoretical, Mathematical and Computational Physics.
Mathematical Physics.
Online Access:Texto Completo
Table of Contents:
  • Introduction
  • Background
  • Development of a new model for simulating the electrical action potentials of human atrial myocytes
  • Development of a family of regional cell models
  • Autonomic regulation and pathophysiological remodelling
  • 3D Anatomical Modelling of the Atria
  • Pacemaking and autonomic regulation in the 3D sinoatrial node and atria
  • Atrial Fibrillation
  • Discussion.

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