Drugs Targeting B-Cells in Autoimmune Diseases

This book provides a detailed overview of B-cell directed therapies in patients with rheumatic and systemic autoimmune diseases, including rheumatoid arthritis, systemic lupus erythematosus, Sjögren syndrome, ANCA-associated vasculitis and cryoglobulinemia. Organ-specific autoimmune diseases are di...

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Bibliographic Details
Call Number:Libro Electrónico
Corporate Author: SpringerLink (Online service)
Other Authors: Bosch, Xavier (Editor), Ramos-Casals, Manuel (Editor), Khamashta, Munther A. (Editor)
Format: Electronic eBook
Language:Inglés
Published: Basel : Springer Basel : Imprint: Springer, 2014.
Edition:1st ed. 2014.
Series:Milestones in Drug Therapy,
Subjects:
Pharmacology.
Immunology.
Rheumatology.
Internal medicine.
Internal Medicine.
Online Access:Texto Completo
Table of Contents:
  • Historic outline of the development of drugs targeting B-cells
  • Understanding B-cell biology
  • Pharmacological effects and mechanisms of action of agents blocking B cells
  • Systemic lupus erythematosus: direct B-cell blocking
  • Systemic lupus erythematosus: indirect B-cell blocking
  • B-cell targeted therapies in rheumatoid arthritis
  • B-cell targeted therapies in Primary Sjögren Syndrome
  • Targeting B cells in ANCA-associated vasculitis
  • B-cell targeted therapies in systemic sclerosis and inflammatory myopathies
  • B-cell targeted therapies in cryoglobulinemia
  • B-cell targeted therapies in autoimmune cytopenias and thrombosis
  • Targeting B cells in neurological autoimmune diseases
  • Targeting B cells in other systemic autoimmune diseases
  • Safety of B-cell targeted therapies
  • The future potential of biosimilars targeting B-cells.

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