The Inflammasomes

The inflammasome was first described in 2002 as a molecular complex activating proinflammatory caspases and therefore regulating the maturation and biological activities of cytokines such as IL-1 and IL-18. This finding was substantiated by the identification of several mutations in the cias1 gene,...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Couillin, Isabelle (Editor ), Pétrilli, Virginie (Editor ), Martinon, Fabio (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Basel : Springer Basel : Imprint: Springer, 2011.
Edición:1st ed. 2011.
Colección:Progress in Inflammation Research,
Temas:
Immunology.
Diseases.
Cytology.
Cytokines.
Enzymology.
Cell Biology.
Cytokines and Growth Factors.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Molecular definition of inflammasomes
  • Pyroptosis: A Caspase-1-dependent programmed cell death and a barrier to infection
  • Activation of the inflammasome by bacterial pathogens
  • The Role of Inflammasomes in Viral Infection
  • Inflammasome activation in response to eukaryotic pathogens
  • Inflammasome activation by pathogenic crystals and particles
  • Inflammasome activation by danger signals
  • Toll like receptors and inflammasomes
  • Inflammasome in the skin
  • Cancer, inflammasomes and adjuvanticity
  • Inflammasome and lung pathologies
  • Mechanisms of NLRP3 inflammasome activation in CAPS patients
  • Activation and regulation of the NLRP3 inflammasome
  • Treatment of inflammasome-related disorders.

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