The Inflammasomes

The inflammasome was first described in 2002 as a molecular complex activating proinflammatory caspases and therefore regulating the maturation and biological activities of cytokines such as IL-1 and IL-18. This finding was substantiated by the identification of several mutations in the cias1 gene,...

Full description

Bibliographic Details
Call Number:Libro Electrónico
Corporate Author: SpringerLink (Online service)
Other Authors: Couillin, Isabelle (Editor), Pétrilli, Virginie (Editor), Martinon, Fabio (Editor)
Format: Electronic eBook
Language:Inglés
Published: Basel : Springer Basel : Imprint: Springer, 2011.
Edition:1st ed. 2011.
Series:Progress in Inflammation Research,
Subjects:
Immunology.
Diseases.
Cytology.
Cytokines.
Enzymology.
Cell Biology.
Cytokines and Growth Factors.
Online Access:Texto Completo
Table of Contents:
  • Molecular definition of inflammasomes
  • Pyroptosis: A Caspase-1-dependent programmed cell death and a barrier to infection
  • Activation of the inflammasome by bacterial pathogens
  • The Role of Inflammasomes in Viral Infection
  • Inflammasome activation in response to eukaryotic pathogens
  • Inflammasome activation by pathogenic crystals and particles
  • Inflammasome activation by danger signals
  • Toll like receptors and inflammasomes
  • Inflammasome in the skin
  • Cancer, inflammasomes and adjuvanticity
  • Inflammasome and lung pathologies
  • Mechanisms of NLRP3 inflammasome activation in CAPS patients
  • Activation and regulation of the NLRP3 inflammasome
  • Treatment of inflammasome-related disorders.

Similar Items