Genomic Elements in Health, Disease and Evolution Junk DNA /

This book provides a thorough review of various non-coding genomic elements and discusses in depth their role in health, disease and evolution. It begins with an exploration of non-coding RNA molecules miRNAs, piRNAs, LncRNAs and transposable elements as these moieties dominate the scientific litera...

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Bibliographic Details
Call Number:Libro Electrónico
Corporate Author: SpringerLink (Online service)
Other Authors: Felekkis, Kyriacos (Editor), Voskarides, Konstantinos (Editor)
Format: Electronic eBook
Language:Inglés
Published: New York, NY : Springer New York : Imprint: Springer, 2015.
Edition:1st ed. 2015.
Subjects:
Medical genetics.
Cytology.
Developmental biology.
Medical Genetics.
Cell Biology.
Developmental Biology and Stem Cells.
Online Access:Texto Completo
Table of Contents:
  • MicroRNAs' function and role in evolution
  • MicroRNAs and disease
  • piRNAs: Transposon silencing and germ line development.-Long non-coding cRNAs
  • Unveiling transposable elements function to enrich knowledge for human physiology and disease pathogenesis
  • Copy number variation in human health, disease and evolution
  • Mini- and micro-satellite markers in health, disease and evolution
  • Intron biology, focusing on group II introns, the ancestors of spliceosomal introns
  • Centromeres in health, disease and evolution
  • Structure and functions of telomeres in organismal homeostasis and disease
  • Proximal regulatory elements with emphasis on CpG rich regions
  • Genomic analysis through high-throughput sequencing.

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