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Design, Analysis, and Interpretation of Genome-Wide Association Scans
This book presents the statistical aspects of designing, analyzing and interpreting the results of genome-wide association scans (GWAS studies) for genetic causes of disease using unrelated subjects. Particular detail is given to the practical aspects of employing the bioinformatics and data handlin...
| Cote: | Libro Electrónico |
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| Auteur principal: | |
| Collectivité auteur: | |
| Format: | Électronique eBook |
| Langue: | Inglés |
| Publié: |
New York, NY :
Springer New York : Imprint: Springer,
2014.
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| Édition: | 1st ed. 2014. |
| Collection: | Statistics for Biology and Health,
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| Sujets: | |
| Accès en ligne: | Texto Completo |
Table des matières:
- Introduction to Genome-Wide Association Studies
- Topics of Quantitative Genetics
- An Introduction to Association Studies
- Correcting for Hidden Population Structure in Single Marker Association Testing and Estimation
- Haplotype Imputation for Association Analysis
- SNP Imputation for Association Studies
- Design of Large-scale Genetic Association Studies, Sample Size and Power
- Post-GWAS Analyses.