Oral Delivery of Macromolecular Drugs Barriers, Strategies and Future Trends /

Due to a rapid development in biotechnology more and more macromolecular drugs such as therapeutic peptides, oligosaccharides and nucleic acids are entering the pharmaceutical arena representing unprecedented challenges from the drug delivery point of view. One of the likely greatest challenges is t...

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Bibliographic Details
Call Number:Libro Electrónico
Corporate Author: SpringerLink (Online service)
Other Authors: Bernkop-Schnürch, Andreas (Editor)
Format: Electronic eBook
Language:Inglés
Published: New York, NY : Springer New York : Imprint: Springer, 2009.
Edition:1st ed. 2009.
Subjects:
Pharmacology.
Biochemistry.
Cytology.
Cell Biology.
Online Access:Texto Completo
Table of Contents:
  • Enzymatic Barriers
  • Gastrointestinal Mucus Gel Barrier
  • The Absorption Barrier
  • Strategies to Overcome the Enzymatic Barrier
  • Low Molecular Mass Permeation Enhancers in Oral Delivery of Macromolecular Drugs
  • Polymeric Permeation Enhancers
  • Strategies to Overcome Efflux Pumps
  • Multifunctional Polymeric Excipients in Oral Macromolecular Drug Delivery
  • Nano- and Microparticles in Oral Delivery of Macromolecular Drugs
  • Liposome-Based Mucoadhesive Formulations for Oral Delivery of Macromolecules
  • Strategies in Oral Immunization
  • Oral Delivery of Nucleic Acid Drugs.

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