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Proteomics and Protein-Protein Interactions Biology, Chemistry, Bioinformatics, and Drug Design /

Gabriel Waksman Institute of Structural Molecular Biology, Birkbeck and University College London, Malet Street, London WC1E 7HX, United Kingdom Address for correspondence: Professor Gabriel Waksman Institute of Structural Molecular Biology Birkbeck and University College London Malet Street London...

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Détails bibliographiques
Cote:Libro Electrónico
Collectivité auteur: SpringerLink (Online service)
Autres auteurs: Waksman, Gabriel (Éditeur intellectuel)
Format: Électronique eBook
Langue:Inglés
Publié: New York, NY : Springer US : Imprint: Springer, 2005.
Édition:1st ed. 2005.
Collection:Protein Reviews ; 3
Sujets:
Accès en ligne:Texto Completo
Table des matières:
  • Introduction: Proteomics and Protein-Protein Interactions: Biology, Chemistry, Bioinformatics, and Drug Design
  • Yeast Two-Hybrid Protein-Protein Interaction Networks
  • The Use of Mass Spectrometry in Studying Protein-Protein Interaction
  • Molecular Recognition in the Immune System
  • Computational Methods for Predicting Protein-Protein Interactions
  • Protein-Protein Docking Methods
  • Thermochemistry of Binary and Ternary Protein Interactions Measured by Titration Calorimetry: Complex Formation of CD4, HIV gp120, and Anti-gp120
  • Protein-Protein Recognition in Phosphotyrosine-Mediated Intracellular Signaling
  • Competitive Binding of Proline-Rich Sequences by SH3, WW, and Other Functionally Related Protein Domains
  • The Structure and Molecular Interactions of the Bromodomain
  • SMART Drug Design: Novel Phosphopeptide and ATP Mimetic-Based Small Molecule Inhibitors of the Oncogenic Protein Kinase pp60src (Src)
  • Disrupting Protein-Protein Interaction: Therapeutic Tools Against Brain Damage
  • A Thermodynamic Guide to Affinity Optimization of Drug Candidates.