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Robustness and Evolvability in Living Systems /
All living things are remarkably complex, yet their DNA is unstable, undergoing countless random mutations over generations. Despite this instability, most animals do not grow two heads or die, plants continue to thrive, and bacteria continue to divide. Robustness and Evolvability in Living Systems...
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| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Woodstock :
Princeton University Press,
2007.
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| Colección: | Book collections on Project MUSE.
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| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Frontmatter
- Contents
- Figures
- Acknowledgments
- 1. Introduction
- 2. The Genetic Alphabet
- 3. The Genetic Code
- 4. RNA Structure
- 5. Proteins and Point Mutations
- 6. Proteins and Recombination
- 7. Regulatory DNA Regions and Their Reorganization in Evolution
- 8. Metabolic Pathways
- 9. Metabolic Networks
- 10. Drosophila Segmentation and Other Gene Regulatory Networks
- 11. Phenotypic Traits, Cryptic Variation, and Human Diseases
- 12. The Many Ways of Building the Same Body
- 13. Neutral Spaces
- 14. Evolvability and Neutral Mutations
- 15. Redundancy of Parts or Distributed Robustness?
- 16. Robustness as an Evolved Adaptation to Mutations
- 17. Robustness as an Evolved Adaptation to Environmental Change and Noise
- 18. Robustness and Fragility: Advantages to Variation and Trade-offs
- 19. Robustness in Natural Systems and Self-Organization
- 20. Robustness in Man-made Systems
- Epilogue: Seven Open Questions for Systems Biology
- Bibliography
- Index.