Bioconjugated materials. Part 2, Applications in drug delivery, vaccine formulations and important conjugates for cancer therapy /
Bioconjugated Materials Part 2, Volume 103 in the Comprehensive Analytical Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters on bioconjugated materials. Each chapter is written by an international board of authors.
Clasificación: | Libro Electrónico |
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Otros Autores: | , |
Formato: | Electrónico eBook |
Idioma: | Inglés |
Publicado: |
Amsterdam :
Elsevier,
2023.
|
Colección: | Comprehensive analytical chemistry ;
103 |
Temas: | |
Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Intro
- Bioconjugated Materials Part 2 Applications in Drug Delivery, Vaccine Formulations and Important Conjugates for Cancer Therapy
- Copyright
- Contents
- Contributors to Volume 103
- About the editors
- Preface
- References
- Series editor's preface
- Chapter One: Multifunctional bioconjugates and their utilities
- 1. Introduction
- 2. Bioconjugation chemistry
- 3. Molecular conjugates
- 3.1. Carbohydrate oligonucleotides conjugates
- 3.2. Lipid oligonucleotides conjugates
- 3.3. Polymeric oligonucleotides conjugates
- 3.4. Antibody oligonucleotides conjugates
- 3.5. Aptamer oligonucleotide conjugates
- 3.6. Small molecule targeting conjugates
- 4. Bioconjugates as functional carriers
- 4.1. Polymer drug conjugates
- 5. Utility of nanobioconjugates in pharmacokinetics
- 6. Future perspectives of bioconjugation
- 7. Conclusions
- Acknowledgements
- References
- Chapter Two: Bioconjugated materials as potential vehicles for delivery of antibiotics/drugs
- 1. Introduction
- 2. Strategies for bioconjugate fabrication
- 2.1. Covalent conjugation
- 2.2. Noncovalent conjugation
- 3. Materials for antibiotics/drugs conjugation
- 3.1. Natural materials for antibiotics/drugs conjugation
- 3.1.1. Pectin
- 3.1.2. Dextran
- 3.1.3. Cellulose
- 3.1.4. Guar gum
- 3.1.5. Pullulan
- 3.1.6. Gum acacia
- 3.2. Synthetic materials for antibiotics/drugs conjugation
- 3.2.1. Polylactic acid (PLA)
- 3.2.2. Poly(lactic-co-glycolic acid) (PLGA)
- 3.2.3. Polycaprolactone
- 3.2.4. Poly(butylene succinate)
- 3.2.5. Polydioxanone (PDS)
- 4. Commercially available materials-conjugated antibiotics/drugs products
- 5. Conclusions and future directions
- Acknowledgements
- Conflicts of interest
- References
- Chapter Three: Bioconjugated materials in the development of subunit vaccines
- 1. Introduction
- 2. Recombinant protein and synthetic peptide-based subunit vaccines
- 2.1. Recombinant protein-based subunit vaccines
- 2.2. Synthetic peptide-based subunit vaccines
- 3. Bioconjugation methods in subunit vaccines
- 3.1. Staudinger ligation reaction
- 3.2. Diels-Alder reaction
- 3.3. N-Hydroxysuccinimide esters
- 3.4. Copper-catalysed alkyne-azide cycloaddition reaction
- 3.5. Strain promoted alkyne-azide cycloaddition
- 4. Bioconjugation materials in subunit vaccines
- 4.1. Polymeric materials as subunit vaccine adjuvants
- 4.1.1. Polysaccharides
- 4.1.1.1. Chitosan and its derivatives in subunit vaccines
- 4.1.1.2. Glucan-based subunit vaccines
- 4.1.1.3. Mannose-containing subunit vaccines
- 4.1.1.4. Insulin-containing subunit vaccines
- 4.1.2. Polyamino acids
- 4.1.3. Synthetic polymers
- 4.2. Lipids in subunit-based vaccines
- 4.2.1. Glycosphingolipids
- 4.2.2. Lipopolysaccharides
- 4.2.3. Lipoproteins and lipopeptides
- 5. Conclusions
- Conflicts of interest
- Funding
- References