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Nanowired delivery of drugs and antibodies for neuroprotection in brain diseases with co-morbidity factors. Part B /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Sharma, Hari Shanker, Wiklund, Lars, Sharma, Aruna
Formato: Electrónico eBook
Idioma:Inglés
Publicado: San Diego : Elsevier Science & Technology, 2023.
Edición:1st ed.
Colección:International review of neurobiology ; v. 172
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Intro
  • Title page
  • Table of Contents
  • Series Page
  • Copyright
  • Contributors
  • Preface
  • References
  • Acknowledgements
  • Section 1 Spinal cord Injury
  • Chapter One: Spinal cord injury induced exacerbation of Alzheimer's disease like pathophysiology is reduced by topical application of nanowired cerebrolysin with monoclonal antibodies to amyloid beta peptide, p-tau and tumor necrosis factor alpha
  • Abstract
  • 1 Introduction
  • 2 Spinal cord injury and Alzheimer's disease
  • 3 Our observation on spinal cord injury and Alzheimer's disease pathology
  • 4 Spinal cord injury and blood-spinal cord barrier
  • 5 Possible mechanism of neuroprotection in spinal cord injury
  • 6 Conclusion and future perspectives
  • References
  • Chapter Two: Nanodelivery of histamine H3 receptor inverse agonist BF-2649 with H3 receptor antagonist and H4 receptor agonist clobenpropit induced neuroprotection is potentiated by antioxidant compound H-290/51 in spinal cord injury
  • Abstract
  • 1 Introduction
  • 2 Nanowired delivery of H-290/51 with histaminergic H3 and H4 receptor modulators in spinal cord injury
  • 3 Our observations in spinal cord injury
  • 4 Blood-spinal cord barrier in spinal cord injury
  • 5 Spinal cord edema and volume swelling in spinal cord injury
  • 6 Spinal cord blood flow in spinal cord injury
  • 7 Oxidative stress parameters in spinal cord injury
  • 8 Neuropathology of spinal cord injury
  • 9 Molecular markers of neuropathology in spinal cord injury
  • 10 Possible mechanisms of neuroprotection in spinal cord injury
  • Acknowledgments
  • References
  • Chapter Three: Neuromodulation and quality of life for patient with spasticity after spinal cord injury
  • Abstract
  • 1 Introduction
  • 2 Materials and methods
  • 3 Results
  • 4 Discussion
  • References
  • Section 2 Neurodegenerative disease.
  • Chapter Four: Efficacy of invasive and non-invasive methods for the treatment of Parkinson's disease: Nanodelivery and enriched environment
  • Abstract
  • 1 Introduction
  • 2 Nanoparticle-drug delivery systems in PD therapeutics
  • 3 Enriched environment as non-invasive strategy for PD treatment
  • 4 Synergistic effect of an enriched environment and nanodelivery administration
  • 5 Concluding remarks
  • References
  • Chapter Five: Co-administration of DL-3-n-butylphthalide and neprilysin is neuroprotective in Alzheimer disease associated with mild traumatic brain injury
  • Abstract
  • 1 Introduction
  • 2 Methodological consideration
  • 3 Our observations on nanowired DL-3-n-butylphthalide in Alzheimer's disease
  • 4 Possible mechanisms of DL-3-n-butylphthalide in neuroprotection in Alzheimer's disease
  • Acknowledgments
  • References
  • Section 3 Drugs of abuse and neurotoxicity
  • Chapter Six: Nicotine neurotoxicity exacerbation following engineered Ag and Cu (50-60 nm) nanoparticles intoxication. Neuroprotection with nanowired delivery of antioxidant compound H-290/51 together with serotonin 5-HT3 receptor antagonist ondansetron
  • Abstract
  • 1 Introduction
  • 2 Our observations on metal nanoparticles exposure and nicotine neurotoxicity
  • 3 Observations on nicotine neurotoxicity with nanoparticles exposure
  • 4 Molecular markers of neuroinflammation
  • 5 Molecular markers of oxidative stress
  • 6 Possible mechanisms of neuroprotection in nicotine neurotoxicity
  • Acknowledgments
  • References
  • Section 4 Clinical neurology and oncology
  • Chapter Seven: Technology of genomic balancing of chromatin of autologous hematopoietic stem cells for gene therapy of fatal immune-mediated diseases of civilization, extended life expectancy and sudden human death prevention
  • Abstract
  • 1 Introduction
  • 2 Description of the proposed technology.