The cardiovascular glycocalyx in health and disease /

The Cardiovascular Glycocalyx in Health and Disease, Volume 91 gives updates on the glycocalyx function through the cardiovascular system and its integration in whole system physiology. Chapters address Endothelial surface layers in the kidney, Pharmacological targeting of the glycocalyx -- current...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Fancher, Ibra S. (Editor ), Chignalia, Andreia Z. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Cambridge, MA : Academic Press is an imprint of Elsevier, 2023.
Colección:Current topics in membranes ; v. 91.
Temas:
Cardiovascular system > Diseases.
Glycocalyces.
Cardiovascular Diseases
Glycocalyx
Appareil cardiovasculaire > Maladies.
Glycocalyx.
Cardiovascular system > Diseases
Glycocalyces
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Intro
  • The Cardiovascular Glycocalyx in Health and Disease
  • Copyright
  • Contents
  • Contributors
  • Preface
  • Chapter One: Impairment of endothelial glycocalyx in atherosclerosis and obesity
  • 1. Introduction
  • 1.1. Major structural components of endothelial glycocalyx
  • 1.2. Major biological functions
  • 2. Impairment of endothelial glycocalyx in atherosclerosis
  • 2.1. Disruption of endothelial glycocalyx in hypercholesterolemic animal models and hypercholesterolemic patients
  • 2.2. Disruption of endothelial glycocalyx by atherogenic lipoproteins
  • 2.3. Disruption of endothelial glycocalyx by proatherogenic disturbed flow
  • 2.4. Pathological consequences of the loss of glycocalyx integrity for atherosclerosis development
  • 2.5. Therapeutic effect of glycocalyx supplementation on atherosclerosis development
  • 3. Effects of obesity on endothelial glycocalyx
  • 4. Conclusion
  • Acknowledgments
  • Reference
  • Chapter Two: The glycocalyx and calcium dynamics in endothelial cells
  • 1. The endothelial glycocalyx
  • 1.1. Structure and composition
  • 2. The glycocalyx in endothelial cell physiology
  • 2.1. The glycocalyx as a regulator of endothelial barrier function
  • 2.2. The glycocalyx in mechano-sensing and the regulation of vascular tone
  • 3. Calcium signaling and endothelial function
  • 3.1. Calcium dynamics in endothelial cells
  • 3.2. The link between the glycocalyx and endothelial calcium signaling
  • 3.3. The endothelial glycocalyx, calcium signaling and cardiovascular disease
  • 4. Conclusions and perspectives
  • Contributions
  • Funding
  • Disclosures
  • References
  • Chapter Three: Mechanotransduction and the endothelial glycocalyx: Interactions with membrane and cytoskeletal proteins t ...
  • 1. Introduction
  • 1.1. Overview of composition, structure, and function of the glycocalyx.
  • 5.5. Fibroblast growth factor
  • 5.6. Heparin
  • 5.7. Sulodexide
  • 5.8. Sevoflurane
  • 5.9. Rhamnan sulfate
  • 5.10. Other drugs that modulate the glycocalyx
  • 6. Conclusions
  • Acknowledgments
  • Author contributions
  • Funding
  • Conflict of interest
  • References
  • Chapter Six: The role of hyaluronan in endothelial glycocalyx and potential preventative lifestyle strategy with advancin ...
  • 1. Introduction
  • 2. Endothelial glycocalyx structure and function
  • 3. Hyaluronan as a primary component of endothelial glycocalyx
  • 4. Endothelial glycocalyx and hyaluronan with aging
  • 5. Preventative lifestyle strategy to maintain healthy endothelial glycocalyx and hyaluronan
  • 6. Conclusion
  • Acknowledgments
  • Author contributions
  • Conflicts of interest
  • Funding
  • References.

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