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SCIDIR_on1376370554 |
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OCoLC |
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20231120010735.0 |
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m o d | |
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cr un|---aucuu |
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221205s2023 enka fob 001 0 eng d |
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|a UKAHL
|b eng
|e rda
|c UKAHL
|d OPELS
|d YDX
|d UKMGB
|d OCLCF
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|a GBC2M4633
|2 bnb
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|a 020838844
|2 Uk
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|a 1375332784
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|a 9780128230558
|q electronic book
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|a 012823055X
|q electronic book
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|z 9780128230268
|q paperback
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|z 9780128230558
|q electronic publication
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|z 0128230266
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|a (OCoLC)1376370554
|z (OCoLC)1375332784
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|a RD33.55
|b .T73 2023
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0 |
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|a 617.05
|2 23/eng/20230501
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|a Translational interventional radiology /
|c edited by Adam E.M. Eltorai, Tao Liu, Rajat Chand, Sanjeeva P. Kalva.
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|a London, United Kingdom :
|b Academic Press,
|c [2023]
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| 300 |
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|a 1 online resource (xviii, 580 pages) :
|b illustrations (some color).
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
0 |
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|a Handbook for designing and conducting clinical and translational research
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| 504 |
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|a Includes bibliographical references and index.
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| 588 |
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|a Description based on online resource; title from digital title page (viewed on June 21, 2023).
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|a <P><b>INTRODUCTION</b> 1. Translational Process; 2. Scientific Method; 3. Basic research </p><b> <p>PRE-CLINICAL: DISCOVERY AND DEVELOPMENT </b>4. Overview of preclinical research; 5. Defining the problem to solve; 6. Types of problems; 7. Types of Interventions; 8. Drug discovery; 9. Drug safety; 10. Device discovery; 11. Device prototyping; 12. Device classification; 13. Device testing; 14. Diagnostic testing; 15. Other product types; 16. Procedural technique development; 17. Behavioral intervention</p><b> <p>CLINICAL: FUNDAMENTALS </b>18. Introduction to clinical research: What is it? Why is it needed?; 19. The question: Types of research questions and how to develop them; 20. Study population: Who and why them?; 21. Outcome measurements: What data is being collected and why?; 22. Optimizing the question: Balancing significance and feasibility </p><b> <p>STATISTICAL PRINCIPLES </b>23. Common issues in analysis; 24. Basic statistical principles; 25. Distributions; 26. Hypotheses and error types; 27. Power; 28. Regression; 29. t-test; 30. Chi-square; 31. Analysis of variance; 32. Correlation; 33. Biases; 34. Basic science statistics</p><b> <p>CLINICAL: STUDY TYPES </b>35. Design principles: Hierarchy of study types; 36. Case series: Design, measures, classic example; 37. Case-control study: Design, measures, classic example; 38. Cohort study: Design, measures, classic example; 39. Cross-section study: Design, measures, classic example; 40. Longitudinal study: Design, measures, classic example; 41. Clinical trials: Design, measures, classic example; 42. Meta-analysis: Design, measures, classic example; 43. Cost-effectiveness analysis: Design, measures, classic example; 44. Diagnostic test evaluation: Design, measures, classic example; 45. Reliability study: Design, measures, classic example; 46. Surveys and questionnaires: Design, measures, classic example; 47. Qualitative methods and mixed methods</p><b> <p>CLINICAL TRIALS </b>48. Randomized control: Design, measures, classic example; 49. Nonrandomized control: Design, measures, classic example; 50. Historical control: Design, measures, classic example; 51. Cross-over: Design, measures, classic example; 52. Withdrawal studies: Design, measures, classic example; 53. Factorial design: Design, measures, classic example; 54. Group allocation: Design, measures, classic example; 55. Large, pragmatic: Design, measures, classic example; 56. Equivalence and noninferiority: Design, measures, classic example; 57. Adaptive: Design, measures, classic example; 58. Randomization: Fixed or adaptive procedures; 59. Blinding: Who and how?; 60. Multicenter considerations; 61. Registries; 62. Phases of clinical trials; 63. IDEAL Framework; 64. Artificial Intelligence; 65. Patient perspectives</p><b> <p>CLINICAL: PREPARATION </b>66. Meaningful outcome measurements; 67. Sample size; 68. Budgeting; 69. Ethics and review boards; 70. Regulatory considerations for new drugs and devices; 71. Funding approaches; 72. Subject recruitment; 73. Data management; 74. Quality control; 75. Statistical software; 76. Report forms: Harm and Quality of Life; 77. Subject adherence; 78. Monitoring committee in clinical trials</p><b> <p>REGULATORY </b>79. FDA overview; 80. IND; 81. New drug application; 82. Device pathways; 83. Radiation-emitting electronic products; 84. Combination products; 85. Cosmetics; 86. CMC and GxP; 87. Non-US regulatory; 88. Post-Market Drug Safety Monitoring; 89. Post-Market Device Safety Monitoring</p><b> <p>CLINICAL IMPLEMENTATION </b>90. Implementation Research; 91. Design and analysis; 92. Mixed-methods research; 93. Population- and setting-specific implementation</p><b> <p>PUBLIC HEALTH </b>94. Public Health; 95. Epidemiology; 96. Good questions; 97. Population- and environmental-specific considerations; 98. Law, policy, and ethics; 99. Healthcare institutions and systems; 100. Public health institutions and systems</p>
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| 650 |
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0 |
|a Interventional radiology.
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| 650 |
|
7 |
|a Interventional radiology.
|2 fast
|0 (OCoLC)fst00977590
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| 700 |
1 |
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|a Eltorai, Adam E. M.,
|e editor.
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| 700 |
1 |
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|a Liu, Tao,
|e editor.
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| 700 |
1 |
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|a Chand, Rajat,
|e editor.
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| 700 |
1 |
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|a Kalva, Sanjeeva P.,
|e editor.
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| 776 |
0 |
8 |
|i ebook version :
|z 9780128230558
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| 776 |
0 |
8 |
|c Original
|z 0128230266
|z 9780128230268
|w (OCoLC)1333078810
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| 856 |
4 |
0 |
|u https://sciencedirect.uam.elogim.com/science/book/9780128230268
|z Texto completo
|
