Cargando…

Essentials of pharmatoxicology in drug research. Volume 1, Toxicity and toxicodynamics /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Tekade, Rakesh K. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London ; San Diego, CA : Academic Press, an imprint of Elsevier, [2023]
Colección:Advances in pharmaceutical product development and research series.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • 1 Understanding pharmacotoxicology
  • 2 Toxicology in drug research
  • 3 Role of microRNAs in toxicology
  • 4 Exosomes as mediators of chemical-induced toxicity
  • 5 Drug-induced oxidative stress as a mechanism of toxicity
  • 6 Role of "toxicant-induced loss of tolerance" in the emergence of disease
  • 7 Types of cellular responses to chemical toxicants
  • 8 Toxicant-induced injury and tissue repair
  • 9 Computer-aided technologies in drug discovery and toxicity prediction
  • 10 Predicting toxicity from chemical structure of a drug compound
  • 11 Toxicokinetics and organ-specific toxicity
  • 12 Drug-induced nephrotoxicity and its biomarkers
  • 13 Mechanism of drug-induced neurotoxicity and its management
  • 14 Thermal processing and food-related toxicants
  • 15 Medication errors and approaches for its prevention
  • 16 Understanding the bioaccumulation of pharmaceuticals and personal care products
  • 17 Toxicity of dental materials and ways to screen their biosafety
  • 18 Clinical detoxification of the body from chemical toxicants
  • 19 Molecular mechanisms of the chemopreventive role of dietary phytochemicals
  • 20 Toxicity labels
  • 21 Toxic potential indicator
  • 22 Concept of pharmacotherapy and managed care in clinical interventions
  • 23 Understanding the connection between dietary supplementation and inadvertent doping
  • 24 Cells and tissue-based models as a rational substitute in toxicity testing
  • 25 Regulatory agencies for toxicological studies
  • 26 Key challenges for toxicologists in the 21st century