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Precision medicine in neurodegenerative disorders. Part I /
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Amsterdam, Netherlands :
Elsevier,
[2023]
|
| Colección: | Handbook of clinical neurology ;
v. 192. |
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- The definition of precision medicine in neurodegenerative disorders and the one disease-many-diseases tension
- Models of precision medicine for neurodegeneration
- Pathology vs pathogenesis: Rationale and pitfalls in the clinicopathology model of neurodegeneration
- Mixed pathology as a rule, not exception: Time to reconsider disease nosology?
- Neurodegenerative disorders: From clinicopathology convergence to systems biology divergence
- The emergence of genotypic divergence and future precision medicine applications
- Lessons from other fields of medicine, Part 1: Breast cancer
- Lessons from other fields of medicine, Part 2: Cystic fibrosis
- Lessons learned from evolving frameworks in adult glioblastoma
- Finding the falsification threshold of the toxic proteinopathy hypothesis in neurodegeneration
- The theoretical problems of "prodrome" and "phenoconversion" in neurodegeneration
- The dilemma between milestones of progression vs. clinical scales in Parkinson disease
- Biomarkers of diagnosis, prognosis, pathogenesis, response to therapy: Convergence or divergence? Lessons from Alzheimer Disease and synucleinopathies
- Challenges in the study of individuals at risk for Parkinson disease
- The challenging quest of neuroimaging: From clinical to molecular-based subtyping of Parkinson disease and atypical parkinsonisms