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|a Precision medicine in neurodegenerative disorders.
|n Part I /
|c edited by Alberto J. Espay.
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|a Amsterdam, Netherlands :
|b Elsevier,
|c [2023]
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|c �2023
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|a 1 online resource (xviii, 269 pages) :
|b illustrations
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|a Handbook of clinical neurology ;
|v volume 192
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|a Includes bibliographical references and index.
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|a Online resource; title from PDF title page (ProQuest, viewed September 22, 2023).
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|t The definition of precision medicine in neurodegenerative disorders and the one disease-many-diseases tension --
|t Models of precision medicine for neurodegeneration --
|t Pathology vs pathogenesis: Rationale and pitfalls in the clinicopathology model of neurodegeneration --
|t Mixed pathology as a rule, not exception: Time to reconsider disease nosology? --
|t Neurodegenerative disorders: From clinicopathology convergence to systems biology divergence --
|t The emergence of genotypic divergence and future precision medicine applications --
|t Lessons from other fields of medicine, Part 1: Breast cancer --
|t Lessons from other fields of medicine, Part 2: Cystic fibrosis --
|t Lessons learned from evolving frameworks in adult glioblastoma --
|t Finding the falsification threshold of the toxic proteinopathy hypothesis in neurodegeneration --
|t The theoretical problems of "prodrome" and "phenoconversion" in neurodegeneration --
|t The dilemma between milestones of progression vs. clinical scales in Parkinson disease --
|t Biomarkers of diagnosis, prognosis, pathogenesis, response to therapy: Convergence or divergence? Lessons from Alzheimer Disease and synucleinopathies --
|t Challenges in the study of individuals at risk for Parkinson disease --
|t The challenging quest of neuroimaging: From clinical to molecular-based subtyping of Parkinson disease and atypical parkinsonisms
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|a Nervous system
|x Degeneration.
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|a Precision medicine.
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|a Neurodegenerative Diseases
|x therapy
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|a Precision Medicine
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|a M�edecine de pr�ecision.
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|a Nervous system
|x Degeneration
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|a Espay, Alberto J.,
|e editor.
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|i Print version:
|t Precision medicine in neurodegenerative disorders. Part I.
|d Amsterdam : Elsevier, 2023
|z 9780323855389
|w (OCoLC)1376270027
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830 |
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|a Handbook of clinical neurology ;
|v v. 192.
|
856 |
4 |
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|u https://sciencedirect.uam.elogim.com/science/handbooks/00729752/192
|z Texto completo
|