Biomarkers of hip implant function /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: �Swi�atkowska, Ilona (Editor )
Formato: eBook
Idioma:Inglés
Publicado: London : Academic Press, 2023.
Temas:
Artificial hip joints > Complications.
Artificial hip joints > Complications > Prevention.
Biochemical markers.
Biomarkers
Marqueurs biologiques.
Artificial hip joints > Complications
Biochemical markers
Electronic books.
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Front Cover
  • Biomarkers of Hip Implant Function
  • Copyright Page
  • Contents
  • List of contributors
  • I. Foundational information
  • 1 Introduction to hip implants and biomarker testing
  • 1.1 Overview of the hip joint
  • 1.1.1 Anatomy of the hip
  • 1.1.1.1 Cartilage
  • 1.1.1.2 Joint capsule and synovial fluid
  • 1.1.1.3 Ligaments
  • 1.1.1.4 Muscles
  • 1.1.1.5 Blood supply and innervation
  • 1.1.2 Hip joint pathologies
  • 1.1.2.1 Osteoarthritis
  • 1.1.2.2 Rheumatoid arthritis
  • 1.1.2.3 Hip dysplasia
  • 1.1.2.4 Avascular necrosis
  • 1.1.2.5 Femoroacetabular impingement
  • 1.1.2.6 Traumatic injuries
  • 1.2 Overview of hip implants
  • 1.2.1 Implant biomaterials
  • 1.2.1.1 Metals
  • 1.2.1.2 Plastic polymers
  • 1.2.1.3 Ceramics
  • 1.2.2 Bone fixation
  • 1.2.3 Implant classification
  • 1.2.4 Evolution of a total hip replacement
  • 1.2.4.1 Implant modularity
  • 1.2.5 The rise and fall of hip resurfacing
  • 1.2.6 Implant degradation
  • 1.2.7 Implant performance
  • 1.2.7.1 Surgeon factors
  • 1.2.7.2 Implant factors
  • 1.2.7.3 Patient factors
  • 1.3 Introduction to biomarkers
  • 1.3.1 Biomarker discovery
  • 1.3.2 Assay validation
  • 1.3.3 Evaluation of clinical validity
  • 1.3.3.1 Sensitivity and specificity
  • 1.3.3.2 Predictive values
  • 1.3.3.3 Likelihood ratios
  • 1.3.3.4 Diagnostic accuracy
  • 1.3.3.5 Receiver operating characteristic curves
  • 1.3.3.6 Diagnostic odds ratios
  • 1.3.4 Characteristics of an ideal biomarker
  • 1.3.5 Biomarkers of hip implant function and toxicity
  • References
  • 2 Degradation of metal hip implants
  • 2.1 Introduction to metallic biomaterials
  • 2.1.1 Iron-based alloys
  • 2.1.2 Cobalt-based alloys
  • 2.1.3 Titanium-based alloys
  • 2.2 Introduction to tribology
  • 2.2.1 Contact of surfaces
  • 2.2.2 Friction
  • 2.2.3 Wear of materials
  • 2.2.3.1 Abrasive wear
  • 2.2.3.2 Adhesive wear
  • 2.2.3.3 Fretting/fatigue wear
  • 2.2.4 Lubrication
  • 2.2.4.1 Boundary lubrication
  • 2.2.4.2 Fluid-film lubrication
  • 2.2.4.3 Mixed lubrication
  • 2.2.4.4 Lubrication in metal hips
  • 2.3 Introduction to corrosion
  • 2.3.1 Thermodynamics and electrochemistry
  • 2.3.2 Passivity of metallic materials
  • 2.3.3 Types of corrosion
  • 2.3.3.1 Uniform/general corrosion
  • 2.3.3.2 Galvanic corrosion
  • 2.3.3.3 Crevice corrosion
  • 2.3.3.4 Pitting corrosion
  • 2.3.3.5 Intergranular corrosion
  • 2.4 Tribocorrosion
  • 2.5 Modern hip replacements
  • 2.5.1 Sources of degradation
  • 2.5.1.1 Bearing surfaces
  • 2.5.1.2 Modular tapers
  • 2.5.1.3 Stem-cement interface
  • 2.5.2 Adverse reaction to metal debris
  • 2.5.3 Assessing material loss from metal hip implants
  • 2.5.4 Studying metal deposits in tissue
  • 2.5.4.1 Periprosthetic tissue
  • 2.5.4.2 Organ tissue
  • 2.6 Summary and future directions
  • References
  • 3 Implant metals and their potential toxicity
  • 3.1 Hip implant metals and the human health
  • 3.1.1 Cobalt
  • 3.1.1.1 Toxicokinetics
  • 3.1.1.2 Systemic toxicity
  • 3.1.2 Chromium

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