Cargando…
Inflammasome biology : fundamentals, role in disease states, and therapeutic opportunities /
Inflammasome Biology: Fundamentals, Role in Disease States, and Therapeutic Opportunities is a complete reference on the role of inflammasomes in health and disease. Sections cover the different types of inflammasomes, including cellular signaling, structural and evolutive aspects, overview the role...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
[S.l.] :
Academic Press,
2022.
|
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- <B>Part I
- Fundamentals of Inflammasome Biology</b> <br>1. Overview of inflammatory processes at cellular level<br>2. Inflammasome formation and triggers<br>3. Cellular signaling, molecular activation and regulation of the NLRP1 inflammasome<br>4. Cellular signaling, molecular activation and regulation of the NLRP3 inflammasome<br>5. Cellular signaling, molecular activation and regulation of the NLRP6 inflammasome<br>6. Cellular signaling, molecular activation and regulation of the NLRC4 inflammasome<br>7. Cellular signaling, molecular activation and regulation of the AIM2 inflammasome<br>8. Cellular signaling, molecular activation and regulation of the Pyrin inflammasome<br>9. Cellular signaling, molecular activation and regulation of the non-canonical inflammasome<br>10. Cellular signaling, molecular activation and regulation of auto-active inflammasomes<br>11. Autophagy and the inflammasome<br>12. Inflammasome effector functions<br>13. Inflammatory caspases<br>14. Structural aspects of inflammasomes<br>15. Evolutive aspects of inflammasomes<br><br><b>Part II
- inflammasome role in disease processes <br></b>16. The inflammasome in cardiovascular diseases <br>17. Inflammasome implications in metabolic disorders <br>18. Inflammasome in venous thromboembolic disorders <br>19. Inflammasomes and neurodegenerative diseases<br>20. Inflammasome implication in diseases of the respiratory system<br>21. Inflammasomes and their regulation in oral disease <br>22. Inflammasomes in inflammatory bowel disease pathogenesis <br>23. Inflammasome induced inflammation and fibrosis in liver<br>24. Inflammasomes in sepsis<br>25. The Inflammasome in viral, bacterial and fungal infections<br>26. Autoinflammatory syndromes<br>27. The inflammasome in graft-versus-host disease<br>28. Implication of the inflammasomes in rheumatic diseases<br>29. The inflammasomes in kidney disease<br>30. Inflammasomes and cancer<br>31. Inflammasomes in the pathobiology of degenerative retinopathies.<br><br><b>Part III
- Inflammasome crosstalk in Cell Death <br></b>32. Regulation of pyroptosis by inflammasomes.<br>33. Crosstalk between necroptosis and inflammasome.<br>34. Apoptosis and inflammasome regulation<br>35. Implication of inflammasomes regulating different types of cell death<br>36. Regulation of neutrophil NETosis by inflammasomes<br><br><b>Part IV
- Therapeutic Opportunities</b> <br>37. Therapeutic opportunities targeting the inflammasome<br>38. Development of selective inflammasome Inhibitors<br>39. Natural compounds blocking inflammasomes<br>40. Inhibitors targeting inflammasome effectors<br>41. Multi-inflammasome inhibitors