Nutrition and cancer /
Clasificación: | Libro Electrónico |
---|---|
Otros Autores: | , |
Formato: | Electrónico eBook |
Idioma: | Inglés |
Publicado: |
Cambridge, MA :
Academic Press,
2022.
|
Colección: | International review of cell and molecular biology ;
v. 373. |
Temas: | |
Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Intro
- Nutrition and Cancer
- Copyright
- Contents
- Contributors
- Emergent impact of lifestyle on tumor progression and response to therapy
- Acknowledgments
- Conflict of interest
- References
- Chapter One: Modifying dietary amino acids in cancer patients
- 1. Introduction
- 2. Reducing availability of NEAAs as an anti-cancer approach
- 3. Role of essential AAs in cancer biology
- 4. Altering dietary protein to limit tumor growth and enhance cancer therapy
- 5. Role of bacteria in mediating the pro-tumorigenic effects of dietary AAs
- 6. Current recommendations for protein intake in cancer patients
- 7. Considerations for evaluating the impact of modifying AA intake on treatment response and outcomes in patients with cancer
- Acknowledgments
- Conflicts of interest
- References
- Chapter Two: Targeting amino acid metabolism in cancer
- 1. Introduction
- 2. Asparagine
- 2.1. Asparagine synthetase (ASNS)
- 2.1.1. Catalytic function and structure of ASNS
- 2.1.2. ASNS deficiency
- 2.1.3. ASNS regulation
- 2.2. L-asparaginase (ASNase)
- 2.2.1. ASNase in leukemias and lymphomas
- 2.2.2. ASNase in solid tumors
- 2.2.3. Glutaminase activity of ASNase
- 2.2.4. Limits of the ASNase therapy
- 3. Arginine
- 3.1. Metabolism of arginine
- 3.2. Arginine-nitric oxide pathway
- 3.3. Arginine-ornithine-polyamine pathway
- 3.4. Suitable candidates for arginine-depleting enzyme therapies
- 3.5. Arginine deiminase
- 3.5.1. Arginine deiminase-based therapy
- 3.5.2. Limitations of arginine deiminase therapy
- 3.6. Arginase
- 3.6.1. Arginase therapy
- 3.6.2. Limitations of arginase therapy
- 4. Methionine
- 4.1. Methionine metabolism
- 4.2. The Hoffman effect
- 4.3. Methioninase
- 4.3.1. Methioninase therapy
- 5. Cysteine
- 5.1. Cysteine metabolism
- 5.2. Cyst(e)inase
- 5.2.1. Cyst(e)inase therapy
- 6. Concluding remarks
- Acknowledgments
- References
- Chapter Three: Fasting and cancer: from yeast to mammals
- 1. Introduction
- 2. Calorie restriction
- 3. Fasting and fasting mimicking diets
- 4. Fasting mimicking diets and cancer
- 4.1. Differential stress resistance
- 4.2. Differential stress sensitization
- 4.3. FMD and antitumor immunity
- 5. Fasting-mimicking diets and non-toxic interventions to kill cancer cells
- 5.1. FMD synergizes with high-dose vitamin C to kill KRAS-mutant cancer cells
- 5.2. FMD cycles potentiate hormone therapies and induce breast cancer regression
- 6. Fasting-mimicking diets in clinical oncology
- Acknowledgments
- References
- Chapter Four: Fasting and cancer responses to therapy
- 1. Introduction
- 2. Nutrients restriction in rodents and humans
- 3. Calorie restriction in cancer therapy
- 4. Alternative approaches to fasting and CR in cancer therapy
- 5. Conclusion
- Acknowledgments
- Conflicts of interest
- Authors contribution
- References