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|a Advances in clinical chemistry.
|n Volume 109 /
|c edited by Gregory S. Makowski.
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| 264 |
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1 |
|a Amsterdam :
|b Academic Press,
|c 2022.
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| 300 |
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|a 1 online resource
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
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|a ISSN
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| 500 |
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|a Includes index.
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|a Print version record.
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|a 6. Summary and future perspectives -- Author contributions -- Conflicts of interest -- References -- Chapter Four: Oligoclonal bands: An immunological and clinical approach -- 1. Introduction -- 2. Evolution in the techniques and detection methods of IgG OCBs -- 2.1. Electrophoresis (EP) on agarose gel -- 2.2. Isoelectric focusing (IEF) technique -- 2.3. Sensitivity and specificity of the immunodetection methods based on EP on agarose gel and IEF -- 2.4. Commercial kits for detection of IgG OCBs -- 3. Determination of IgG OCBs within the diagnostic criteria of MS: An overview -- 4. IEF as reference technique in IgG OCBs detection -- 5. A single band of IgG immunoglobulin in CSF -- 6. Prevalence of IgG OCBs and effect of latitude in MS -- 7. OCBs of IgM isotype: An overview -- 7.1. Introduction -- 7.2. Evolution in the techniques and detection methods -- 7.3. Clinical and immunological significance of IgM OCBs -- 8. Clinical usefulness of IgG OCBs in neurological diseases -- 9. Summary and future perspectives -- References -- Chapter Five: Immunoassay design and biotin interference -- 1. Introduction -- 2. Biotin: Overview of pharmacology -- 3. Biotin supplements -- 4. Serum biotin -- 5. Biotin based immunoassays and biotin interference -- 6. Clinically significant interferences due to elevated biotin concentrations -- 7. Biotin interference in thyroid testing -- 8. Biotin interference in PTH testing -- 9. Biotin interference in troponin testing -- 10. FDA communication on biotin -- 11. Biotin interference in multiple immunoassays -- 12. Threshold biotin concentration for interference -- 13. Prevalence of clinically significant biotin interference -- 14. Mitigation of biotin interference -- 15. Conclusions -- References -- Chapter Six: Orexin/hypocretin and major psychiatric disorders -- 1. Introduction -- 2. Orexin and narcolepsy -- 3. Schizophrenia.
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|a 3.1. Clinical studies -- 3.2. Antipsychotics -- 3.2.1. Animal studies -- 3.2.2. Clinical studies -- 3.3. Psychotic polydipsia -- 3.3.1. Animal studies -- 3.3.2. Clinical studies -- 4. Major Depressive Disorder (MDD) -- 4.1. Animal studies -- 4.1.1. Genetic -- 4.1.2. Early life stress (ELS) -- 4.1.3. Treatment during adulthood -- 4.1.3.1. Social defeat model -- 4.1.3.2. Unpredictable chronic mild stress (UCMS) -- 4.1.3.3. Orexin injection -- 4.1.3.4. Other models -- 4.1.4. Animal studies on Orexin receptors -- 4.2. Clinical studies -- 4.3. Medications -- 5. Bipolar disroder -- 6. Other studies -- 7. Conclusion -- Acknowledgment -- References -- Index.
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| 650 |
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|a Clinical chemistry.
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| 650 |
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2 |
|a Chemistry, Clinical
|0 (DNLM)D002624
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| 650 |
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6 |
|a Chimie clinique.
|0 (CaQQLa)201-0016714
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| 650 |
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7 |
|a Clinical chemistry
|2 fast
|0 (OCoLC)fst00864330
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| 700 |
1 |
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|a Makowski, Gregory S.
|q (Gregory Stephen),
|e editor.
|1 https://isni.org/isni/0000000107166351
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| 776 |
0 |
8 |
|i Print version:
|t Advances in clinical chemistry. Volume 109.
|d Amsterdam : Academic Press, 2022
|z 9780323988513
|w (OCoLC)1332951505
|
| 856 |
4 |
0 |
|u https://sciencedirect.uam.elogim.com/science/bookseries/00652423/109
|z Texto completo
|
