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Microbiome, immunity, digestive health and nutrition epidemiology, pathophysiology, prevention and treatment /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Bagchi, Debasis, 1954-, Downs, Bernard W.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London : Academic Press, 2022.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Front Cover
  • Microbiome, Immunity, Digestive Health and Nutrition
  • Copyright Page
  • Dedication
  • Contents
  • List of contributors
  • Preface
  • I. Microbiome and Human Health: An Introduction
  • 1 Oral microbiome: a gateway to your health
  • 1.1 Introduction
  • 1.2 Oral microbiome and oral disease
  • 1.2.1 Caries
  • 1.2.2 Periodontal disease
  • 1.2.3 Oral cancer
  • 1.3 Oral microbiome and systemic disease
  • 1.3.1 Alzheimer's disease
  • 1.3.2 Cardiovascular disease
  • 1.3.3 Diabetes
  • 1.4 Concluding remarks
  • Acknowledgments
  • References
  • 2 Influence of microbiome in shaping the newborn immune system: an overview
  • 2.1 Introduction
  • 2.2 How the microbiota shapes the development of immunity in early life
  • 2.3 Influence of the microbiota on the development and function of specific immune cell subsets in early life
  • 2.3.1 Myeloid cells
  • 2.3.1.1 Erythrocytes in the spleen
  • 2.3.1.2 Myeloid-derived suppressor cells
  • 2.3.2 Lymphoid cells
  • 2.3.2.1 T cell repertoire
  • 2.3.2.2 CD4+ T cells
  • 2.3.2.3 Th1 and Th2 Cells
  • 2.3.2.4 Th17 cells
  • 2.3.2.5 T regulatory cells
  • 2.3.2.6 CD8+ T cells
  • 2.3.2.7 Innate-like lymphocytes
  • 2.3.2.7.1 Invariant natural killer T cells
  • 2.3.2.8 Innate lymphoid cells
  • 2.3.2.8.1 NK cells
  • 2.3.2.9 B cells
  • 2.3.3 Epithelial cells
  • 2.4 Conclusion
  • Author disclosure statement
  • References
  • 3 Impact of the gut microbiome on human health and diseases
  • 3.1 Introduction
  • 3.1.1 Definition of microbiome
  • 3.1.2 Uneven distribution of microbiota across various sites and organs of the body: reasons and implications
  • 3.2 The gut as the most significant niche of the human microbiome
  • 3.2.1 Establishment of the gut microbiome: journey from womb to adulthood
  • 3.2.2 Heritable component of the gut microbiome
  • 3.2.3 Role of diet and other environmental factors in shaping the gut microbiome
  • 3.3 Physiological roles of the gut microbiome
  • 3.3.1 Gut Microbiota in metabolism
  • 3.3.2 Gut microbiota in boosting immune response: role of short-chain fatty acids and cross-talk with diet
  • 3.3.3 The role of the gut microbiome in the development of gut-associated lymphoid tissue
  • 3.3.4 Gut microbes as a defense mechanism against pathogens
  • 3.3.5 Role in cognitive development: the gut-brain axis
  • 3.3.6 The gut microbiome as a human organ
  • 3.4 Dysbiosis of normal flora: implications in human diseases and intervention strategies
  • 3.4.1 Gut microbiome in human ailments
  • 3.4.1.1 Obesity
  • 3.4.1.2 Diabetes
  • 3.4.1.3 Hypertension
  • 3.4.1.4 Cancer
  • 3.4.1.5 Inflammatory bowel disease
  • 3.4.1.6 Gout
  • 3.4.1.7 Depression
  • 3.4.1.8 Rheumatoid arthritis
  • 3.4.1.9 Infant health
  • 3.4.2 How to keep the gut happy: prebiotics, probiotics, postbiotics, and synbiotics
  • 3.5 Concluding remarks
  • Acknowledgments
  • References