Unraveling the complexities of metastasis : transition from a segmented view to a conceptual continuum /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Farooqi, Ammad Ahmad, Zhaid Qureshi, Muhammad, Sabitaliyevi, Uteuliyev Yerzhan
Formato: eBook
Idioma:Inglés
Publicado: London, UK : Academic Press, 2022.
Temas:
Metastasis.
Neoplasm Metastasis
M�etastases.
Metastasis
Acceso en línea:Texto completo
Tabla de Contenidos:
  • 2
  • Multiple roles of circulating tumor cells and exosomes in cancer metastasis: implications for therapeutic inter ...
  • Introduction
  • CTCs involvement in metastatic progression
  • Strategies for isolation and enrichment of CTCs
  • Characterization of CTCs
  • Exosomes involvement in metastatic progression
  • Strategies for detection, isolation, and enrichment of exosomes
  • Characterization of exosomes
  • Clinical impact of CTCs and exosomes
  • Conclusions and future perspectives
  • References
  • 3
  • Diagnosis and treatment of metastatic prostate cancer: the role of imaging, liquid biopsies, and biomarkers for ...
  • Introduction
  • Overview of prostate cancer disease states and treatment options
  • Proliferative inflammatory atrophy
  • Localized prostate cancer and treatment options
  • Metastatic castration-resistant prostate cancer and treatment options
  • Improved imaging and image-guided biopsy for prostate cancer
  • Imaging signatures of hypoxia
  • Gene signature panels for prostate cancer risk stratification
  • Next-generation sequencing and prostate cancer: cell-free nucleic acids and circulating tumor cells
  • Conclusion
  • Acknowledgments
  • References
  • 4
  • Prognostic and predictive role of bone metastasis in NSCLC: risk factors and clinical implications
  • Introduction
  • Incidence of BMs in NSCLC patients
  • Prognostic role
  • Localization of BMs
  • Histology and driver mutations
  • Development of complications and performance status
  • Treatments
  • Predictive role
  • Risk factors for bone metastasis
  • Prognostic factors and predictive factors for bone progression
  • Predictive factors for SRE development
  • Clinical implication and treatment
  • Conclusion
  • References
  • 5
  • Brain metastases in breast cancer
  • Introduction
  • The basis of breast cancer brain metastasis
  • The metastatic cascade
  • Brain microenvironment and BC
  • Neuroinflammation role in metastasis
  • Signaling pathways involved in BM from BC
  • Differences between the primary tumor cells and BM
  • Risk factors for brain metastasis in breast cancer
  • Diagnosis
  • Treatment
  • Prognosis
  • Specific conditions
  • Brain metastasis from breast cancer in BRCA mutation carriers

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