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Combinational therapy in triple negative breast cancer /
| Clasificación: | Libro Electrónico |
|---|---|
| Autor principal: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
London, United Kingdom :
Academic Press,
2022.
|
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Front cover
- Half title
- Copyright
- Contents
- Contributors
- About the author
- Foreword
- Preface
- Acknowledgment
- Chapter 1
- Triple-negative breast cancer
- an aggressive subtype of breast cancer
- Introduction
- Triple-negative breast cancer (TNBC)
- TNBC histological classification
- TNBC molecular classification
- BL-1 and BL-2
- M subtype
- MSL subtype
- IM subtype
- LAR subtype
- TNBC and BRCA
- Triple-negative breast cancer risk factors and epidemiology
- Current diagnostic options for triple-negative breast cancer
- Mammography
- Ultrasound
- Magnetic resonance imaging (MRI)
- Future diagnostic options for TNBC
- Blood-based liquid biopsy
- Circulating tumor nucleic acids (ctNAs)
- Exosomes
- Immuno-positron emission tomography (PET)
- Nanobiosensor
- nCounter breast cancer 360 panel
- Digital polymerase chain reaction (dPCR)
- Triple-negative breast cancer's prognostic implications
- Somatic genomic mutations in TNBC
- Epigenetic modifications in TNBC
- Methylation of DNA in triple-negative breast cancer
- Relation between DNA methylation and TNBC progression
- Role of long noncoding RNAs in TNBC
- Role of MicroRNA in TNBC
- Role of histone modifications in TNBC
- Summary
- References
- Chapter 2
- Novel biomarkers in triple-negative breast cancer
- role and perspective
- Introduction
- Triple-negative breast cancer: Genetic markers
- TP53
- BRCA1/2
- PI3K pathway
- Androgen receptor
- BCL2 gene
- Cyclin-dependent kinases
- Triple-negative breast cancer: Novel biomarkers
- EGFR
- VEGF
- C-kit and basal cytokeratins
- TOP-2A
- Ki67
- PARP
- Heat shock protein 90
- Cox-2
- Epigenetic modifications in TNBC as novel biomarkers
- Tissue miRNAs as biomarkers in TNBC