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Stromal signaling in cancer /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Angel, Peggi M., Ostrowski, Michael C.
Formato: eBook
Idioma:Inglés
Publicado: Cambridge, MA : Academic Press, 2022.
Colección:Advances in cancer research ; v. 154.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Intro
  • Stromal Signaling in Cancer
  • Copyright
  • Contents
  • Contributors
  • Preface
  • Chapter One: The pathologic diagnosis of carcinoma in various tissues
  • 1. Introduction
  • 2. Breast carcinoma
  • 3. Colorectal carcinoma
  • 4. Lung carcinoma
  • 5. Pancreatic carcinoma
  • 5.1. Liver
  • 6. Hepatocellular carcinoma
  • 7. Prostate carcinoma
  • 8. Central nervous system malignancy
  • References
  • Chapter Two: Predictive value of collagen in cancer
  • 1. Introduction
  • 2. Breast cancer
  • 2.1. Prostate adenocarcinoma
  • 3. Lung cancer
  • 4. Hepatocellular carcinoma (liver cancer)
  • 5. Colon cancer
  • 6. Pancreatic cancer
  • 7. Perspectives and conclusions
  • Acknowledgments
  • Author contributions
  • References
  • Chapter Three: Molecular sensors for detection of tumor-stroma crosstalk
  • 1. Introduction
  • 2. Force biosensors
  • 2.1. The role of mechanical stimuli on tumor growth and metastasis
  • 2.2. Principles of molecular force probes
  • 2.3. Application of molecular force probes
  • 3. Imaging reporters for single-cell kinase signaling
  • 3.1. Kinase translocation reporter biosensors
  • 3.2. FRET-based biosensors for studying kinase signaling
  • 4. Biosensors for detection of cellular metabolic activity
  • 4.1. Monitoring glucose uptake in tumors
  • 4.1.1. (18)F-fluorodeoxyglucose
  • 4.1.2. 2-[N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino]-2-deoxy-d-glucose
  • 4.2. Biosensors for detecting intracellular ATP levels
  • 4.2.1. PercevalHR
  • 4.2.2. ATeam
  • 4.2.3. BTeam
  • 4.2.4. iATPSnFR
  • 4.3. Biosensors for detecting intracellular glucose levels
  • 4.3.1. Green Glifons
  • 4.3.2. Fluorescent glucose/galactose binding protein
  • 4.4. Biosensors for detecting NAD+
  • 4.5. Other metabolic sensors
  • 4.5.1. Pyruvate
  • 4.5.2. Lactate and 2-oxoglutarate
  • 5. Detecting cell-cell interactions.