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|a 0323907423
|q (electronic bk.)
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|a 571.9/685
|2 23
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|a One, no one, one hundred thousand :
|b the multifaceted role of macrophages in health and disease.
|n Part A /
|c Edited by Samanta A. Mariani, Luca Cassetta, Lorenzo Galluzzi.
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|a Cambridge, UK :
|b Academic Press is an imprint of Elsevier,
|c 2022.
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|a 1 online resource
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|a International review of cell and molecular biology ;
|v v. 367
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|a Intro -- One, No one, One Hundred Thousand -- The Multifaceted Role of Macrophages in Health and Disease -- Part A -- Copyright -- Contents -- Contributors -- Chapter One: Pulmonary macrophages and SARS-Cov2 infection -- 1. Introduction -- 2. Macrophages in the healthy lung -- 2.1. Alveolar macrophages -- 2.2. Interstitial macrophages -- 3. Inflammation as a driver of COVID-19 severity -- 4. Macrophage as mediators of organ damage in COVID-19? -- 4.1. Defining the macrophage compartment in COVID-19 -- 4.2. The role of macrophage subsets in SARS-CoV-2 infection -- 5. Targeting the macrophage in severe COVID-19: Current and future therapeutics? -- Acknowledgments -- References -- Chapter Two: Macrophage control of Crohn�s disease -- 1. Introduction -- 2. Development of intestinal macrophages -- 3. Localization and heterogeneity of intestinal macrophages -- 4. Functional properties of intestinal macrophages -- 5. Maintenance of homeostatic macrophage function -- 6. Macrophages in Crohn�s disease -- 7. Macrophages contribute to in intestinal inflammation in CD -- 8. Macrophage functions and dysfunctions in Crohn�s disease -- 9. Targeting macrophages to improve Crohn�s disease -- Acknowledgments -- References -- Chapter Three: Metabolism in tumor-associated macrophages -- 1. Introduction -- 2. Glucose metabolism -- 2.1. Regulation of glucose metabolism in TAMs -- 2.2. Glucose metabolism in TAM function -- 3. Amino acid metabolism -- 3.1. Regulation of amino acid metabolism -- 3.2. Amino acid metabolism in TAM function -- 4. Lipid metabolism in TAM -- 4.1. Fatty acid metabolism -- 4.2. Arachidonic acid metabolism -- 4.3. Cholesterol metabolism -- 5. Targeting TAM metabolism for therapy -- 6. Conclusion -- References -- Chapter Four: Macrophages in the kidney in health, injury and repair -- 1. Introduction -- 2. Identification of renal macrophages.
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|a 3. Ontology of renal macrophage and their role in the developing kidney -- 3.1. Developmental origin of kidney macrophages -- 3.2. Roles of macrophages in kidney development -- 4. Macrophage phenotypic heterogeneity -- 4.1. Macrophage activation states -- 4.2. Mononuclear phagocyte phenotyping in the era of single cell RNA sequencing -- 4.3. Single cell RNA sequencing in the healthy kidney -- 4.4. Single cell RNA sequencing studies in kidney disease -- 5. Role of macrophages in renal immunosurveillance -- 6. Macrophages in renal injury -- 6.1. Pro-inflammatory macrophages predominate during acute kidney injury -- 6.2. Macrophage activation in chronic kidney disease -- 6.3. Macrophage to myofibroblast transition -- 7. Macrophages in renal repair -- 8. Therapeutic prospects -- 9. Conclusions -- References -- Chapter Five: Heterogeneity and function of macrophages in the breast during homeostasis and cancer -- 1. Introduction -- 2. Mammary gland macrophages -- 2.1. Development and structure of the mammary gland -- 2.2. Macrophage heterogeneity in the mammary gland -- 2.3. Localization and role of macrophages in the mammary gland -- 3. Breast cancer -- 4. Macrophages in breast cancer -- 4.1. Macrophage heterogeneity in breast cancer -- 4.2. Impact of hypoxia on the heterogeneity and functions of TAMs in breast cancer -- 5. Concluding remarks and future perspectives -- Competing interests -- Funding -- References -- Chapter Six: Endometrial macrophages in health and disease -- 1. Introduction -- 2. Endometrial physiology -- 3. Endometrial macrophages-Origin, location and abundance -- 4. Identification and characterization of endometrial macrophages -- 5. Regulation of macrophage function during the menstrual cycle -- 5.1. Decidualization -- 5.2. Menstruation -- 6. Endometrial macrophages in women�s reproductive health disorders.
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|a 6.1. Macrophages in endometriosis -- 6.2. Macrophages in abnormal uterine bleeding -- 7. Future directions -- 8. Conclusions -- Acknowledgments -- Conflict of interest -- References.
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|a Macrophages.
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|a Macrophages
|2 fast
|0 (OCoLC)fst01005265
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|a Mariani, Samanta A.
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|a Cassetta, Luca.
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|a Galluzzi, Lorenzo.
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|c Original
|z 0323907415
|z 9780323907415
|w (OCoLC)1284287490
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|u https://sciencedirect.uam.elogim.com/science/bookseries/19376448/367
|z Texto completo
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