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|a Immunotherapeutics /
|c Edited by Rossen Donev.
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|a Cambridge, MA :
|b Academic Press,
|c 2022.
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|a 1 online resource (1 volume)
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|a text
|b txt
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|a computer
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|a online resource
|b cr
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|a Advances in protein chemistry and structural biology ;
|v 129
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|a Print version record.
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|a Intro -- Immunotherapeutics -- Copyright -- Contents -- Contributors -- Chapter One: In silico tools and databases for designing cancer immunotherapy -- 1. Introduction -- 2. Cancer associated genomic data -- 2.1. Genome profile repositories -- 2.2. Mutation profile databases -- 2.3. Cancer biomarker repositories -- 3. Immunological database -- 4. Analysis of genomic profiles -- 5. Prediction of cancer biomarkers -- 6. Identification of vaccine candidates -- 6.1. B-cell epitope -- 6.2. MHC binders -- 6.3. T-cell epitope -- 6.4. Cytokines inducing peptides -- 6.5. Neoepitope for cancer
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|a 7. Important pipelines -- 7.1. HLA typing -- 7.2. Neoantigen -- 8. Cancer-specific immunotherapy -- 9. Miscellaneous -- 10. Discussion and conclusion -- Acknowledgments -- References -- Chapter Two: Immunotherapeutic approaches for HPV-caused cervical cancer -- 1. Introduction -- 2. HPV -- 2.1. Structure -- 2.2. HPV types -- 2.3. Viral life cycle and pathogenesis -- 2.4. Immune response to HPV infection -- 3. Vaccines -- 4. HPV therapeutic vaccines -- 4.1. Peptide-/protein-based vaccines -- 4.2. Vector-based vaccines -- 4.3. Nano-delivery systems -- 4.4. DNA-based vaccines
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|a 4.5. RNA-based vaccines -- 4.6. Cell-based vaccines -- 4.6.1. Dendritic cell-based vaccines -- 4.6.2. Tumor-cell-based vaccines -- 4.6.3. Adoptive T-cell therapy -- 4.7. Therapeutic HPV vaccines in combination with therapeutic modalities -- 4.7.1. Therapeutic HPV vaccines accompanied by immune checkpoint blockade -- 4.7.2. Therapeutic HPV vaccines along with chemo-immunotherapy and radiotherapy -- 4.7.3. Therapeutic HPV vaccines in combination with other treatment modalities -- 5. Conclusion -- Funding -- Conflicts of interest -- References
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|a Chapter Three: Natural killer cell-based strategies for immunotherapy of cancer -- 1. Natural killer cells origin and functions -- 2. NK cell recognition in health and disease -- 2.1. NK cell receptor families -- 2.1.1. C-type lectin-like receptors -- 2.1.2. Killer immunoglobulin-like receptors -- 2.1.3. Natural cytotoxicity receptors -- 3. NK cells as a tool of cancer immunotherapy -- 3.1. Cancer immunosurveillance -- 3.2. Mechanisms of tumor escape from NK cell immunosurveillance -- 4. NK cell-based immunotherapeutics -- 4.1. Activated NK cell-based therapeutics
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|a 4.2. Recombinant protein-based NK cell therapeutics -- 4.3. Gene-modified NK cell-based therapeutics -- 5. Concluding remarks -- Acknowledgments -- References -- Chapter Four: Noncoding RNAs as novel immunotherapeutic tools against cancer -- 1. Introduction -- 2. Immunotherapy in human diseases -- 3. Immunotherapy in cancer -- 4. Noncoding RNAs in cancer -- 4.1. Reprogramming of macrophage differentiation & function by ncRNAs -- 4.2. Modulation of natural killer cell mediated cytotoxicity by ncRNAs -- 4.3. Regulation of neutrophil plasticity & activity by ncRNAs
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|a Immunotherapy.
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650 |
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2 |
|a Immunotherapy
|0 (DNLM)D007167
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650 |
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|a Immunoth�erapie.
|0 (CaQQLa)201-0067406
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650 |
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7 |
|a Immunotherapy.
|2 fast
|0 (OCoLC)fst00968044
|
700 |
1 |
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|a Donev, Rossen,
|e editor.
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776 |
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8 |
|i Print version:
|t IMMUNOTHERAPEUTICS.
|d [Place of publication not identified] : ELSEVIER ACADEMIC PRESS, 2022
|z 0323992277
|w (OCoLC)1264711987
|
856 |
4 |
0 |
|u https://sciencedirect.uam.elogim.com/science/bookseries/18761623/129
|z Texto completo
|