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SCIDIR_on1304815228 |
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220322s2022 enk o 000 0 eng d |
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|a YDX
|b eng
|c YDX
|d OPELS
|d EBLCP
|d OCLCO
|d OCLCF
|d OCLCQ
|d SFB
|d OCLCQ
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019 |
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|a 1305011308
|a 1305169877
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|a 9780128214619
|q (electronic bk.)
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|a 0128214619
|q (electronic bk.)
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|z 9780128214466
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|z 0128214465
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|a (OCoLC)1304815228
|z (OCoLC)1305011308
|z (OCoLC)1305169877
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050 |
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4 |
|a RC685.A65
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082 |
0 |
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|a 616.128
|2 23
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|a Torsades de pointes /
|c [edited by] James E. Tisdale.
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|a London :
|b Academic Press,
|c 2022.
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300 |
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|a 1 online resource
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|a Print version record.
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|a Intro -- Torsades de Pointes -- Copyright -- Dedication -- Contents -- Contributors -- Preface -- Chapter 1: Overview of torsades de pointes -- Introduction -- Definitions and descriptions of TdP -- Defining TdP -- ECG characteristics of TdP -- Historical perspectives -- Evolving understanding on mechanisms of TdP -- Pathophysiology of TdP -- Genesis of TdP -- Perpetuation of TdP -- Spotlight on: Canine models of TdP -- Overview of LQTS and TdP -- Relationship between LQTS and TdP -- Introduction to inherited and acquired QT interval prolongation -- Inherited QT interval prolongation
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505 |
8 |
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|a Acquired QT interval prolongation -- Interplay of inherited and acquired factors in LQTS -- Epidemiology of TdP -- Overall rates of prolonged QTc interval and TdP -- Inherited LQTS and TdP -- Inherited LQTS -- Inherited TdP -- Acquired LQTS and TdP -- Acquired LQTS -- Acquired TdP -- Consequences of LQTS and TdP -- Symptoms of LQTS and TdP -- Spotlight on: Treatment of inherited LQTS -- Prognosis -- Prognosis in patients with inherited LQTS -- Prognosis in patients with acquired LQTS -- Future directions -- References -- Chapter 2: Torsades de pointes associated with inherited channelopathies
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|a Introduction -- Long QT syndrome -- Acquired LQTS and the link to congenital LQTS -- Torsades de pointes arrhythmias -- Therapeutic options for torsades de pointes -- Short-coupled torsades de pointes arrhythmia -- Therapeutic options for short-coupled torsades de pointes -- Conclusions -- References -- Chapter 3: Drug-induced torsades de pointes -- Introduction -- Medications as a cause of TdP -- Drug-induced QT interval prolongation and prediction of TdP risk -- Determining causality for drug-induced QT interval prolongation and TdP: The adverse drug event causality analysis (ADECA) ...
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|a Evidence requirements for risk categories -- Scientific validation of the QTdrugs list and the ADECA process -- Frequency of prescription of QT interval-prolonging medications -- Epidemiology of TdP and death associated with QT interval-prolonging drugs -- Management of risk of drug-induced QT prolongation and TdP -- Conclusion -- References -- Chapter 4: Mechanisms of torsades de pointes -- Introduction -- A brief introduction to ventricular action potential electrogenesis, including INa, IKs, and IKr -- Drugs linked to torsades de pointes in humans and the association with IKr/hERG block
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|a A role for pharmacological activation of late sodium current in diLQTS -- IKs and repolarization reserve -- Cellular arrhythmogenic events resulting from action potential prolongation: Early afterdepolarizations -- How is torsades de pointes initiated and maintained? -- Insights from genetically altered animal models of LQTS -- Insights into mechanisms of torsades de pointes from models used to study drug-induced long QT syndrome -- Constructing an integrated mechanistic description of torsades de pointes: Is there a final necessary mechanism?
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650 |
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0 |
|a Arrhythmia.
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650 |
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0 |
|a Arrhythmia
|x Chemotherapy.
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650 |
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2 |
|a Arrhythmias, Cardiac
|0 (DNLM)D001145
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650 |
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6 |
|a Arythmie.
|0 (CaQQLa)201-0019194
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650 |
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6 |
|a Arythmie
|0 (CaQQLa)201-0019194
|x Chimioth�erapie.
|0 (CaQQLa)201-0379519
|
650 |
|
7 |
|a Arrhythmia.
|2 fast
|0 (OCoLC)fst00815084
|
650 |
|
7 |
|a Arrhythmia
|x Chemotherapy.
|2 fast
|0 (OCoLC)fst00815085
|
700 |
1 |
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|a Tisdale, James E.,
|e editor.
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776 |
0 |
8 |
|i ebook version :
|z 9780128214619
|
776 |
0 |
8 |
|c Original
|z 0128214465
|z 9780128214466
|w (OCoLC)1220993432
|
776 |
0 |
8 |
|i Print version:
|t TORSADES DE POINTES.
|d [S.l.] : ELSEVIER ACADEMIC PRESS, 2021
|z 0128214465
|w (OCoLC)1220993432
|
856 |
4 |
0 |
|u https://sciencedirect.uam.elogim.com/science/book/9780128214466
|z Texto completo
|