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RAS : past, present, and future /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Cambridge, MA : Academic Press, 2022.
Colección:Advances in cancer research ; v. 153.
Temas:
Acceso en línea:Texto completo

MARC

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245 0 0 |a RAS :  |b past, present, and future /  |c Edited by John P. O'Bryan, Gary A. Piazza. 
264 1 |a Cambridge, MA :  |b Academic Press,  |c 2022. 
300 |a 1 online resource (1 volume) 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 1 |a Advances in cancer research ;  |v volume 153 
588 0 |a Print version record. 
505 0 |a 1. A brief history of RAS and the RAS Initiative; Frank McCormick ; 2. Not all RAS mutations are equal: A detailed review of the functional diversity of RAS hot spot mutations; Rachel A. Burge and G. Aaron Hobbs ; 3. Drug targeting opportunities en route to Ras nanoclusters; Karolina Pavic, Rohan Chippalkatti, and Daniel Abankwa ; 4. Targeting the ERK mitogen-activated protein kinase cascade for the treatment of KRAS-mutant pancreatic cancer; J. Nathaniel Diehl, Priya S. Hibshman, Irem Ozkan-Dagliyan, Craig M. Goodwin, Sarah V. Howard, Adrienne D. Cox, and Channing J. Der ; 5. Pan-RAS inhibitors: Hitting multiple RAS isozymes with one stone; Alexander B. Coley, Antonio Ward, Adam B. Keeton, Xi Chen, Yulia Maxuitenko, Aishwarya Prakash, Feng Li, Jeremy B. Foote, Donald J. Buchsbaum, and Gary A. Piazza ; 6. Targeting RAS oncogenesis with SOS1 inhibitors; Roman Christian Hillig and Benjamin Bader ; 7. Inhibition of SHP2 as an approach to block RAS-driven cancers; Yu-Ting Chou and Trever G. Bivona ; 8. Targeting the "undruggable#x94; RAS with biologics; Michael Whaby, Imran Khan, and John P. O'Bryan ; 9. Unraveling and targeting RAS-driven metabolic signaling for therapeutic gain; Jonathan M. DeLiberty, Ryan Robb, Claire E. Gates, and Kirsten L. Bryant ; 10. The RASopathies: Biology, genetics and therapeutic options; Jody Fromm Longo and Steven L. Carroll 
650 0 |a Ras oncogenes. 
650 2 |a Genes, ras  |0 (DNLM)D011905 
650 6 |a Oncog�enes ras.  |0 (CaQQLa)201-0203645 
650 7 |a Ras oncogenes  |2 fast  |0 (OCoLC)fst01090193 
776 0 8 |i Print version:  |t RAS.  |d [Place of publication not identified] : ELSEVIER ACADEMIC PRESS, 2022  |z 0128244852  |w (OCoLC)1260665727 
830 0 |a Advances in cancer research ;  |v v. 153. 
856 4 0 |u https://sciencedirect.uam.elogim.com/science/bookseries/0065230X/153  |z Texto completo