Imidazole-based drug discovery /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Agarwal, Shikha (Autor)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam, Netherlands ; Oxford, United Kingdom ; Cambridge, MA, United States : Elsevier, [2022]
Colección:Heterocyclic drug discovery.
Temas:
Imidazoles.
Drugs.
Drug development.
Imidazoles
Pharmaceutical Preparations
Imidazole.
M�edicaments.
M�edicaments > D�eveloppement.
Drug development
Drugs
Acceso en línea:Texto completo
Tabla de Contenidos:
  • 2.3.5 Using benzil, aldehyde, and ammonium acetate
  • 2.4 Tetra-substituted imidazole derivatives
  • 2.4.1 Using aminoethylpiperazine
  • 2.4.2 Using prop-2-ynylamine
  • 2.4.3 Using benzil, aldehydes, ammonium acetate, and aniline
  • 3 Imidazole hybrids
  • 3.1 Imidazole fused heterocycles
  • 3.2 Benzimidazole fused heterocycles
  • 4 Benzimidazole
  • 4.1 Hoebrecker synthesis
  • 4.2 Synthesis of benzimidazoles using o -phenylenediamine and acids
  • 4.3 Synthesis of benzimidazoles using o -phenylenediamine and acid anhydride
  • 4.4 Synthesis of benzimidazoles using o -phenylenediamine and alcohols
  • 4.5 Synthesis of benzimidazoles using o -phenylenediamine and alkyl halides
  • 4.6 Synthesis of benzimidazoles using ketones
  • 4.7 Synthesis of benzimidazoles using o -phenylenediamine and aldehydes
  • 5 Conclusion
  • Conflict of interest
  • Acknowledgments
  • Funding source
  • References
  • Chapter 2 Biological profile of imidazole-based compounds as anticancer agents
  • 1 Introduction
  • 2 Imidazole-based heterocycles
  • 2.1 Imidazole as the main nucleus in the anticancer compounds
  • 2.1.1 Mono-substituted imidazole derivatives
  • 2.1.2 Disubstituted imidazole derivatives
  • 2.1.3 Trisubstituted imidazole derivatives
  • 2.1.4 Tetra-substituted imidazole derivatives
  • 2.2 Imidazole hybrids as anticancer agents
  • 2.3 Imidazole fused heterocycles
  • 2.3.1 Imidazole fused heterocycles
  • 2.3.2 Benzimidazole fused heterocycles
  • 2.4 Imidazole-based metal complexes as anticancer agents
  • 3 Conclusion and future challenges
  • Conflict of interest
  • Acknowledgment
  • Funding source
  • References
  • Chapter 3 Recent advancements on imidazole containing heterocycles as antitubercular agents
  • 1 Introduction
  • 2 Imidazole-based heterocycles
  • 2.1 Substituted imidazoles
  • 2.2 Hybrid Imidazoles
  • 2.3 Fused imidazoles
  • 2.4 Linker imidazole
  • 2.5 Benzimidazole
  • 3 Conclusion
  • Conflict of interest
  • Acknowledgments
  • Funding source
  • References
  • Chapter 4 Imidazole derivatives: Impact and prospects in antiviral drug discovery
  • 1 Introduction
  • 2 Imidazole derivatives and their action against different viruses
  • 2.1 Zika virus
  • 2.2 Influenza
  • 2.3 SARS-COVID
  • 2.4 Dengue
  • 2.5 Hepatitis
  • 2.6 HIV
  • 2.7 Miscellaneous
  • 3 Conclusion
  • Acknowledgments
  • Conflict of interest
  • Funding source
  • References

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