Tabla de Contenidos:
  • Front Cover
  • Lanzkowsky's Manual of Pediatric Hematology and Oncology
  • Copyright Page
  • Dedication
  • Contents
  • List of contributors
  • About the Editors
  • Philip LanzkowskyFounding Author and Editor
  • Jonathan D. Fish Managing Editor
  • Jeffrey M. Lipton
  • Preface to the seventh edition
  • Preface to the sixth edition
  • Preface to the fifth edition
  • Preface to the fourth edition
  • Preface to the third edition
  • Preface to the second edition
  • Preface to the first edition
  • Introduction: Historic perspective (1955-2015)
  • Reflection on 60 years of progress in pediatric hematology/oncology
  • 1 Molecular and genomic methodologies for clinicians
  • Clinical molecular and genomic methodologies: goals
  • Methods of genetic analysis
  • Markers of genetic defects
  • Sequencing approaches
  • Sanger sequencing
  • Next-generation sequencing technologies and applications
  • Interpretation of genetic variants obtained from next-generation sequencing
  • Applications of next-generation sequencing to oncology
  • Clinical interpretation of sequence variants in cancer
  • Liquid tumor biopsies
  • Epigenetic sequencing
  • Single-cell sequencing
  • Interpreting and evaluating the results from clinical genetic testing
  • Further reading and references
  • 2 Hematologic manifestations of systemic illness
  • Alterations to red blood cells related to organ-specific pathologies
  • Cardiovascular system
  • Anemia
  • Erythrocytosis
  • Qualitative changes to RBC morphology
  • Lungs
  • Anemia
  • Erythrocytosis
  • Gastrointestinal tract
  • Anemia
  • Pancreas
  • Anemia
  • Liver
  • Anemia
  • Kidneys
  • Anemia
  • Endocrine system
  • Anemia
  • Erythrocytosis
  • Skin
  • Eczema and psoriasis
  • Dermatitis herpetiformis
  • Dyskeratosis congenita
  • Alterations to white blood cells related to organ-specific pathologies
  • Cardiovascular system
  • Gastrointestinal tract
  • Spleen
  • Endocrine system
  • Skin
  • Mast cell disease
  • Alterations to platelets and coagulation related to organ-specific pathologies
  • Cardiovascular system
  • Gastrointestinal tract
  • Liver
  • Thrombocytopenia
  • Coagulation abnormalities
  • Skin
  • Ehlers-Danlos syndrome
  • General considerations for the hematologic sequelae of infection
  • Anemia
  • White cell alterations
  • Clotting abnormalities
  • Thrombocytopenia
  • Viral and bacterial illnesses associated with marked hematologic sequelae
  • Parvovirus
  • Epstein-Barr virus
  • TORCHES infections
  • Salmonella typhi
  • Acute infectious lymphocytosis
  • Bartonellosis
  • Tuberculosis
  • Leptospirosis (Weil disease)
  • Severe acute respiratory syndrome coronavirus 2
  • Human immunodeficiency virus
  • Thrombocytopenia
  • Anemia and neutropenia
  • Coagulation abnormalities
  • Role of hematopoietic growth factors in treatment of AIDS-associated cytopenia
  • Cancers in children with human immunodeficiency virus infection
  • HIV-associated lymphoma
  • Proliferative lesions of mucosa-associated lymphoid tissue.