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|a 1280459898
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|a Effects of peri-adolescent licit and illicit drug use on the developing CNS.
|n Part I /
|c edited by Richard L. Bell, Shafiqur Rahman.
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| 260 |
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|a Cambridge, MA :
|b Academic Press,
|c 2021.
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|a 1 online resource
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|a text
|b txt
|2 rdacontent
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|a online resource
|b cr
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| 490 |
1 |
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|a International review of neurobiology ;
|v volume 160
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|a Print version record.
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|a Intro -- Effects of Peri-Adolescent Licit and Illicit Drug Use on the Developing CNS Part I -- Copyright -- Contents -- Contributors -- Preface -- Peri-adolescent addiction as a public health issue -- Neurodevelopment during adolescence and emerging adulthood -- Adolescent timing in rodents -- The addiction cycle -- Learning and memory -- Chapters in Part I of the special issue -- References -- Chapter One: The persistent impact of adolescent binge alcohol on adult brain structural, cellular, and behavioral pathol ... -- 1. Introduction
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8 |
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|a 1.1. Alcohol use in human adolescents increases risk for developing an alcohol use disorder in adulthood -- 1.2. Adolescent intermittent ethanol (AIE) exposure increases adult drinking -- 2. Brain maturation during adolescence creates a window of vulnerability for injury -- 2.1. Adolescent maturation of neurocircuitry -- 2.2. Adolescent maturation of brain glia -- 3. Persistent changes in adult brain after adolescent binge alcohol -- 3.1. Long-lasting changes in MRI-assessed structure -- 3.2. Cellular changes in brain after adolescent binge drinking -- 3.3. Loss of adult neurogenesis
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| 505 |
8 |
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|a 3.4. Lasting changes in adult brain gene expression -- 3.5. Adolescent alcohol exposure-induced changes in adult behavior -- 4. Neuroimmune signaling and epigenetic mechanisms -- 4.1. Microglial memory -- 4.2. Microglia, intoxication, and priming during withdrawal -- 4.3. Neuronal and glial neuroimmune signaling -- 4.4. Immune signaling and histone modifications with transcriptional silencers and enhancers -- 4.5. Epigenetic cholinergic neuronal phenotype loss and trophic-proinflammatory balance
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| 505 |
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|a 5. Reversibility of persistent adolescent alcohol pathology: Exercise, anti-inflammatories, and promotion of cholinergic ... -- 6. Adolescent alcohol abuse as a possible risk factor for cognitive decline with aging -- 7. Conclusion -- References -- Chapter Two: Neuroepigenetic consequences of adolescent ethanol exposure -- 1. Introduction -- 2. Epigenetic modifications -- 3. Ethanol�s metabolic influence on epigenetics -- 4. Ethanol-induced epigenetic alterations in the amygdala -- 5. Ethanol-induced epigenetic alterations in the prefrontal cortex
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|a 6. Ethanol-induced epigenetic alterations in the hippocampus -- 7. Conclusion and future directions -- Acknowledgments -- References -- Chapter Three: Trajectories of brain development reveal times of risk and factors promoting resilience to alcohol use dur ... -- 1. Epidemiology of alcohol use in adolescence -- 2. Overview of factors associated with alcohol misuse in adolescence -- 3. Alcohol use during adolescence: Its effect on brain structure and function -- 3.1. Brain structural disturbance -- 3.2. Brain functional impairments -- 3.3. Short conclusion -- 4. Resilience and brain mechanisms
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| 650 |
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|a Neuropharmacology.
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| 650 |
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|a Teenagers
|x Drug use.
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| 650 |
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2 |
|a Neuropharmacology
|0 (DNLM)D009480
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| 650 |
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6 |
|a Neuropharmacologie.
|0 (CaQQLa)201-0038270
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| 650 |
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7 |
|a Neuropharmacology
|2 fast
|0 (OCoLC)fst01036458
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| 650 |
|
7 |
|a Teenagers
|x Drug use
|2 fast
|0 (OCoLC)fst01145579
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| 700 |
1 |
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|a Bell, Richard L.,
|d 1961-
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| 700 |
1 |
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|a Rahman, Shafiqur,
|d 1963-
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| 776 |
0 |
8 |
|i Print version:
|z 9780128208069
|
| 776 |
0 |
8 |
|i Print version:
|t Effects of peri-adolescent licit and illicit drug use on the developing CNS. Part I.
|d Cambridge, MA : Academic Press, 2021
|z 0128208058
|z 9780128208052
|w (OCoLC)1245658958
|
| 776 |
0 |
8 |
|i Print version:
|t EFFECTS OF PERI-ADOLESCENT LICIT AND ILLICIT DRUG USE ON THE DEVELOPING CNS.
|d [S.l.] : ELSEVIER ACADEMIC PRESS, 2021
|z 0128208058
|w (OCoLC)1245658958
|
| 830 |
|
0 |
|a International review of neurobiology ;
|v v. 160.
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| 856 |
4 |
0 |
|u https://sciencedirect.uam.elogim.com/science/bookseries/00747742/160
|z Texto completo
|
