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Bioinformatics : methods and applications /

Systems biology is an emerging field to study the complex interactions in biological systems. The enormous amount of data generated through high-throughput technologies allows the reconstruction of the biological pathways in a structured and dynamic way at the systems level. Hence, for understating...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Singh, Dev Bukhsh, Pathak, Rajesh Kumar
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London : Academic Press, 2021.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Introduction to basics of bioinformatics
  • Biological databases and their application
  • Biological sequence analysis
  • Genome assembly and annotation
  • Computational molecular phylogeny: concepts and applications
  • Applications and challenges of microarray and RNA-sequencing
  • RNA-seq for revealing the function of the transcriptome
  • Analysis of SSR and SNP markers
  • Gene ontology: application and importance in functional annotation of the genomic data
  • Metagenomics: the boon for microbial world knowledge and current challenges
  • Protein structure prediction
  • Structural and functional analysis of protein
  • Computational approaches in drug designing
  • Structure-based drug designing
  • Ligand-based drug designing
  • Discovery and optimization of lead molecules in drug designing
  • Pharmacophore modeling and its applications
  • Molecular docking and molecular dynamics simulation
  • Pharmacokinetics and pharmacodynamics analysis of drug candidates
  • Computational approaches for vaccine designing
  • Metabolomics and flux balance analysis
  • Topological parameters, patterns, and motifs in biological networks
  • Network biology and applications
  • Pathway modeling and simulation analysis
  • Systems biology and big data analytics
  • Machine learning in bioinformatics
  • Bioinformatics and biological data mining.