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|a 616.81
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|a Brain protection strategies and nanomedicine /
|c edited by Hari Shanker Sharma, Aruna Sharma.
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|a First edition.
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|a Amsterdam, Netherlands ;
|a Cambridge, MA, United States :
|b Elsevier,
|c 2021.
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|a 1 online resource
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
|b cr
|2 rdacarrier
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|a Progress in brain research ;
|v volume 266
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|a Includes bibliographical references.
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|a Online resource; title from digital title page (viewed on November 01, 2021).
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|a Intro -- Progress in Brain Research -- Copyright -- Contributors -- Contents -- Acknowledgments -- Preface -- References -- Chapter 1: Histamine H3 and H4 receptors modulate Parkinson's disease induced brain pathology. Neuroprotective effects of ... -- 1. Introduction -- 1.1. Histaminergic system in the brain -- 1.2. Histaminergic receptors in the brain -- 1.3. Histamine in brain diseases -- 1.3.1. Cognitive dysfunction and Alzheimer's disease -- 1.3.2. Motor disorders and Parkinson's disease -- 1.3.3. Schizophrenia -- 1.3.4. Multiple sclerosis -- 1.3.5. Sleep disorders
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|a 1.3.6. Addictive disorders -- 2. Histaminergic system alterations in Parkinson's disease -- 2.1. Histamine concentration in PD -- 2.2. Histaminergic nerve fibers in PD -- 2.3. Histaminergic gene and receptors in PD -- 2.3.1. HMT and HDC gene expression are altered in PD brain -- 2.3.2. Histamine H3 and H4 receptor expression are altered in PD brain -- 3. Our own investigations on histamine modulation of Parkinson's disease -- 3.1. Methodological consideration -- 3.1.1. Animals -- 3.2. Animal model of PD -- 3.3. Modulation of histaminergic agents
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|a 3.3.1. Histamine H3 receptor inverse agonist BF2649 -- 3.3.2. Histamine H3 receptor antagonist and partial H4 receptor agonist clobenpropit -- 3.3.3. Anti-histamine mouse monoclonal antibody -- 3.3.4. TiO2 nanodelivery of pharmacological agents -- 3.4. Parameters measured -- 3.4.1. Physiological parameters -- 3.4.2. Physiological variables -- 3.4.3. Blood-brain barrier permeability -- 3.4.3.1. Albumin immunohistochemistry -- 3.4.4. Cerebral blood flow -- 3.4.5. Brain edema formation -- 3.5. Behavioral functions -- 3.5.1. Rota Rod treadmill -- 3.5.2. Immobility during forced swimming
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|a 4.1.2. Physiological variables in MPTP model of PD -- 4.1.2.1. Mean arterial blood pressure -- 4.1.2.2. Arterial pH -- 4.1.2.3. Arterial PaCO2 -- 4.1.2.4. Arterial PaO2 -- 4.1.2.5. Heart rate -- 4.1.2.6. Respiration rate -- 4.1.3. Behavioral parameters in MPTP model of PD -- 4.1.3.1. Rota-Rod performance -- 4.1.3.2. Forced swimming immobility -- 4.1.4. Biochemical parameters of MPTP model of PD -- 4.1.4.1. Tyrosine hydroxylase enzyme -- 4.1.4.2. Dopamine -- 4.1.4.3. DOPAC -- 4.1.5. Hallmarks of biomarkers in MPTP model of PD -- 4.1.5.1. ASNC -- 4.1.5.2. p-tau
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|a Brain
|x Diseases.
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650 |
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|a Brain
|x Diseases
|x Treatment.
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|a Nanomedicine.
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2 |
|a Brain Diseases
|0 (DNLM)D001927
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650 |
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|a Cerveau
|x Maladies.
|0 (CaQQLa)201-0001145
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6 |
|a Cerveau
|0 (CaQQLa)201-0001145
|x Maladies
|0 (CaQQLa)201-0001145
|x Traitement.
|0 (CaQQLa)201-0377521
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650 |
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7 |
|a Brain
|x Diseases.
|2 fast
|0 (OCoLC)fst00837607
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650 |
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7 |
|a Brain
|x Diseases
|x Treatment.
|2 fast
|0 (OCoLC)fst00837618
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650 |
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7 |
|a Nanomedicine.
|2 fast
|0 (OCoLC)fst01744350
|
655 |
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4 |
|a Internet Resources.
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655 |
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4 |
|a Index not Present.
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700 |
1 |
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|a Sharma, H. S.
|q (Hari Shanker),
|e editor.
|
700 |
1 |
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|a Sharma, Aruna,
|c MD,
|e editor.
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776 |
0 |
8 |
|i Print version:
|t Brain protection strategies and nanomedicine.
|b First edition.
|d Amsterdam, Netherlands ; Cambridge, MA, United States : Elsevier, 2021
|z 0323989276
|z 9780323989275
|w (OCoLC)1260131978
|
830 |
|
0 |
|a Progress in brain research ;
|v v. 266.
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856 |
4 |
0 |
|u https://sciencedirect.uam.elogim.com/science/bookseries/00796123/266
|z Texto completo
|