Zika virus impact, diagnosis, control, and models. Volume 2, The neuroscience of Zika /

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Martin, Colin R., 1964-, Hollins Martin, Caroline, Preedy, Victor R., Rajendram, Rajkumar
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London : Academic Press, 2021.
Temas:
Zika virus.
Guillain-Barr�e syndrome.
Neurosciences.
Zika Virus
Neurosciences
Guillain-Barre Syndrome
Virus Zika.
Syndrome de Guillain-Barr�e.
Guillain-Barr�e syndrome
Zika virus
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Intro
  • Zika Virus Impact, Diagnosis, Control, and Models
  • Copyright
  • Dedication
  • Contents
  • Contributors
  • Foreword
  • Preface
  • Section A: Zika virus: Setting the scene
  • Chapter 1: How Zika virus emerged and spread worldwide
  • African origin of Zika virus and its dispersion to Asia
  • Introduction of ZIKV in Oceania
  • Introduction of ZIKV in the Americas
  • Reintroduction of ZIKV in Africa
  • Policy and procedures
  • Mini-dictionary of terms
  • Key facts
  • Summary points
  • References
  • Chapter 2: Clinical neurological spectrum of adult and congenital ZIKV infection: An overview of virology, pathogenesis, ...
  • Virology of Zika virus
  • Introduction to Zika virus
  • Epidemiology of Zika virus
  • Pathogenesis of Zika virus
  • Mechanisms of infection
  • Infection via mosquitoes
  • Horizontal transmission within humans
  • Vertical transmission and mechanisms of entry into the nervous system
  • Cross-reactivity and cross-protection between ZIKV and DENV infections
  • Clinical presentation of ZIKV infection
  • Neurological manifestations of ZIKV infection
  • ZIKV-associated Guillain-Barr�e syndrome
  • ZIKV-associated central nervous system involvement
  • Congenital ZIKA syndrome
  • Ophthalmic manifestations of ZIKV
  • Clinical management of ZIKA infections
  • Diagnosis of ZIKA infections
  • Follow-up in pregnant women
  • Treatment of ZIKV infections
  • Possibility of a vaccine for ZIKA?
  • Subsection policy and procedures
  • Screening for ZIKA virus among pregnant women
  • Screening for congenital microcephaly
  • Mini-dictionary of terms
  • Key facts of Zika virus neurological manifestations
  • Key facts of congenital ZIKV syndrome
  • Summary points
  • References
  • Chapter 3: Classification of Zika virus sequences with respect to their species and subspecies
  • Introduction
  • Zika virus sequences from African countries.
  • Zika virus sequences from the Asian region
  • Evolution of the Asian lineage
  • Spread of the Asian lineage to Pacific and Americas
  • The proposition of three lineages
  • Conclusion
  • Policy and procedures
  • Sequencing
  • Classification of sequences
  • Genetic sequence database
  • Mini-dictionary of terms
  • Key facts of Zika virus lineage
  • Summary points
  • References
  • Chapter 4: Health knowledge about Zika virus: Brazil aspects
  • Introduction
  • Public health response on vector control: Communicational strategies and perceptions of risk
  • Advice to delay pregnancy as a public health strategy
  • Awareness and knowledge about Zika virus in Brazil
  • Consequences of the Zika virus epidemics on health services response and on reproductive behaviors
  • Conclusion
  • Policy and procedures
  • Mini-dictionary of terms
  • Key facts of Zika virus knowledge in Brazil
  • Summary points
  • References
  • Chapter 5: Zika virus infection and replication organelle biogenesis
  • Introduction
  • Zika virus infection induces intracellular membrane remodeling and viral replication organelle formation
  • Viral proteins required for viral replication organelle biogenesis
  • ER membrane proteins involved in the formation of viral replication organelle
  • Endosomal sorting complex required for transport-mediated membrane invagination and fission
  • Autophagic machinery is activated in the ZIKV-infected cells
  • Membrane lipids involved in the formation of viral replication organelle
  • Concluding remarks
  • Policy and procedures
  • Mini-dictionary of terms
  • Key facts of virus replication organelle biogenesis
  • Summary points
  • References
  • Section B: Microcephaly and congenital syndromes
  • Chapter 6: Microcephaly: Zika and other congenital infections
  • Microcephaly and TORCH agents
  • Development of microcephaly in congenital infections.
  • Pathogen characteristics
  • Zika virus
  • Rubella virus
  • Toxoplasma gondii
  • Cytomegalovirus
  • The pathogenesis of congenital infections
  • Zika virus
  • Rubella virus
  • Toxoplasma gondii
  • Cytomegalovirus
  • Policy and procedures
  • Mini-dictionary of terms
  • Key facts on microcephaly secondary to intrauterine infections
  • Summary points
  • References
  • Chapter 7: Zika and impact on the nervous system in children
  • Introduction
  • Epidemiology
  • Clinical manifestations
  • Congenital Zika virus infection
  • Neurological complications associated with Zika infection
  • Neuropathogenesis
  • Diagnosis
  • Management
  • Prevention
  • Mini-dictionary of terms
  • Key facts
  • Summary points
  • References
  • Chapter 8: Use of induced pluripotent stem cells and cerebral organoids to profile Zika virus infection: Features and fin ...
  • Introduction
  • Experimental models to study neurological diseases
  • Induced pluripotent stem cells
  • iPSCs X Zika virus
  • Cerebral organoids
  • Cerebral organoids X Zika virus
  • Perspectives and conclusions
  • Policy and procedures
  • Materials and methods
  • Mini-dictionary of terms
  • Key facts
  • Summary points
  • References
  • Chapter 9: Zika, miRNAs, and microcephaly genes
  • Introduction
  • ZIKV-induced cranial morphology
  • Molecular pathogenesis
  • Microcephaly genes
  • ZIKV and miRNAs
  • Microcephaly genes
  • MCPH genes and the miRs connection
  • MCPH mutations and the miR link
  • Summary points
  • References
  • Further reading
  • Chapter 10: Adherens junctions and cell polarity: What they are and how they relate to congenital Zika virus syndrome
  • Cadherin-based adherens junctions and neural development
  • Cell polarity and symmetric versus asymmetric cell division
  • Flaviviruses and their impact on the expression and distribution of cell adhesion molecules.
  • Current knowledge on the impact of N-cadherin-based AJs and apical-basal polarity of RGCs in ZIKV-induced neuropathology
  • Policy and procedures
  • Mini-dictionary of terms
  • Key facts of neurodevelopmental disorders
  • Summary points
  • References
  • Section C: Guillain-Barr�e syndrome
  • Chapter 11: Severe Guillain-Barr�e syndrome
  • Introduction
  • Pathophysiology of Guillain-Barr�e syndrome
  • Clinical presentation
  • Severe GBS
  • Laboratory tests
  • Cerebrospinal fluid analysis
  • Electrodiagnostic studies
  • Antiganglioside antibodies and preceding infections
  • Imaging
  • Treatment
  • IVIG
  • Plasma exchange
  • Combination treatment options
  • Zipper method
  • Policy and procedures: Diagnosis and treatment of Guillain-Barr�e syndrome
  • Treatment
  • Mini-dictionary of terms
  • Key facts of plasma exchange
  • Summary points
  • References
  • Chapter 12: Oxidative stress in Guillain-Barr�e syndrome and linkage with neurology
  • Introduction
  • Oxidative stress in demyelinating diseases
  • Free radicals and enzymatic antioxidation in GBS
  • GBS and lipophilic antioxidants
  • Uric acid, albumin, and haptoglobin as the antioxidant substrate in patients with GBS
  • T cell activity in GBS
  • Policy and procedures
  • Mini-dictionary of terms
  • Key facts of oxidative stress in GBS
  • Summary points
  • References
  • Chapter 13: Neuromuscular effects and rehabilitation in Guillain-Barr�e syndrome
  • Introduction
  • Pharmacological treatment
  • Multidisciplinary rehabilitation
  • Exercise
  • Neuromuscular electrical stimulation
  • Virtual motor rehabilitation system
  • Safety
  • Policy and procedures
  • Neuromuscular electrical stimulation protocol
  • Mini-dictionary of terms
  • Key facts of neuromuscular rehabilitation in GBS
  • Summary points of neuromuscular rehabilitation in GBS
  • References.
  • Chapter 14: Postinfectious demyelinating diseases: Guillain-Barr�e syndrome and beyond
  • Introduction
  • Zika virus and peripheral nervous system inflammatory and demyelinating diseases
  • Zika virus and central nervous system inflammatory and demyelinating diseases
  • Challenges in the diagnosis of ZIKV and the role of other flavivirus infection
  • Conclusions
  • Policy and procedures
  • International classification criteria for inflammatory demyelinating diseases of the central and peripheral nervous system
  • Zika antibody and nucleic acid amplification testing
  • References (related to policy and procedures)
  • Mini-dictionary of terms
  • Key facts
  • Key facts of Zika virus-related neurological disorders
  • Key facts of demyelinating diseases
  • Summary points
  • References
  • Chapter 15: Linking in placental alterations, Zika virus, and Guillain-Barr�e syndrome
  • Introduction
  • The placenta and vertical transmission
  • Placental permissiveness to ZIKV
  • Histopathological aspects and changes in ZIKV-infected placentas
  • Cell subpopulations and cytokines in ZIKV-infected placentas
  • The Guillain-Barr�e syndrome
  • The clinical of GBS
  • The GBS associated with ZIKV infection
  • Conclusion
  • Policy and procedures
  • Mini-dictionary of terms
  • Key facts of ZIKV-infected placentas and GBS associated to ZIKV
  • Summary points
  • References
  • Section D: Case studies and short reports
  • Chapter 16: Case study: Neuroimaging of adults and Zika virus
  • Introduction
  • Case study
  • Acute disseminated encephalomyelitis
  • Imaging findings of acute disseminated encephalomyelitis
  • Acute disseminated encephalomyelitis and Zika virus
  • Conclusion
  • Policy and procedures
  • Mini-dictionary of terms
  • Key facts of Zika virus infection complicated by acute disseminated encephalomyelitis
  • Summary points
  • References.

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