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20231120010551.0 |
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210709s2021 ne o 000 0 eng d |
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|a HUA
|b eng
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|e pn
|c HUA
|d OCLCO
|d OPELS
|d OCLCO
|d OCLCF
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|d UKAHL
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|d OCLCQ
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|a GBC165533
|2 bnb
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|a 020173463
|2 Uk
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|a 1287881906
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|a 0128212780
|q (ePub ebook)
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|a 9780128212783
|q (electronic bk.)
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|z 9780128212776
|q (pbk.)
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|z 0128212772
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|a (OCoLC)1259505292
|z (OCoLC)1287881906
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|a RC280.B8
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|a 616.994061
|2 23
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| 245 |
0 |
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|a Discovery and development of anti-breast cancer agents from natural products /
|c edited by Goutam Brahmachari.
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| 264 |
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1 |
|a Amsterdam :
|b Elsevier,
|c 2021.
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| 300 |
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|a 1 online resource (1 volume)
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| 336 |
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|a text
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
0 |
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|a Natural product drug discovery
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| 505 |
0 |
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|a Cover -- Title -- Copyright -- Dedication -- Contents -- Contributors -- Editor's Biography -- Forewords -- Preface -- Chapter 1 -- Discovery and Development of Anti-Breast Cancer Agents From Natural Products: An Overview -- 1 -- Introduction -- 2 -- An overview of the book -- 2.1 -- Chapter 2 -- 2.2 -- Chapter 3 -- 2.3 -- Chapter 4 -- 2.4 -- Chapter 5 -- 2.5 -- Chapter 6 -- 2.6 -- Chapter 7 -- 2.7 -- Chapter 8 -- 2.8 -- Chapter 9 -- 2.9 -- Chapter 10 -- 2.10 -- Chapter 11 -- 3 -- Concluding remarks
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| 505 |
8 |
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|a Chapter 2 -- Epothilones A and B: The 16-Membered Natural Macrolides as a Fascinating Template for Antibreast Cancer Drug Di... -- 1 -- Introduction -- 2 -- Epothilones A and B: production and isolation, physical and spectral properties, anticancer potential, and mechanism of... -- 2.1 -- Production and isolation -- 2.2 -- Physical and spectral properties -- 2.2.1 -- Epothilone A (1) -- 2.2.2 -- Epothilone B (2) -- 2.3 -- Anticancer potential and mechanism of drug action -- 2.3.1 -- Anticancer potential -- 2.3.2 -- Mechanism of drug action -- 2.3.3 -- Structure-activity relationships (SARs) for epothilones
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| 505 |
8 |
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|a 3 -- The epothilone template: role in anticancer drug discovery -- 4 -- Concluding remarks -- References -- Chapter 3 -- Anti-Breast Cancer Terpenoids of Natural Origins -- 1 -- Introduction -- 1.1 -- Causes of breast cancer -- 1.2 -- Types of breast cancers -- 1.3 -- Breast cancer biomarkers -- 1.4 -- Clinical diagnosis -- 1.5 -- Stages of breast cancer -- 1.6 -- Treatment options -- 2 -- Role of natural products in breast cancer treatment -- 2.1 -- Terpenes as anti-breast cancer agents -- 2.2 -- Sesquiterpenoids as anti-breast cancer agents -- 2.3 -- Diterpenoids as anti-breast cancer agents
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8 |
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|a 2.3.1 -- Paclitaxel as a clinical drug against breast cancer -- 2.3.2 -- Structure-activity relationships (SARs) of paclitaxel -- 2.4 -- Triterpenoids as anti-breast cancer agents -- 2.4.1 -- Ursolic acid as anti-breast cancer agent -- 2.4.2 -- Cucurbitacins as anticancer agents against breast cancer -- 3 -- Future prospects -- 4 -- Concluding remarks -- Abbreviations -- References -- Chapter 4 -- Vinca Alkaloids as Chemotherapeutic Agents Against Breast Cancer -- 1 -- Introduction: an overview of breast cancer -- 2 -- Vinca alkaloids: general features, sources, and ethnopharmacological relevance
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|a 2.1 -- Vinblastine (originally known as vincaleucoblastine) -- 2.2 -- Vincristine (originally known as leurocristine) -- 2.3 -- Vinorelbine -- 2.4 -- Vindesine -- 2.5 -- Vinflunine -- 3 -- Isolation and characterization of vinca alkaloids -- 4 -- Mechanism of action of vinca alkaloids cytotoxicity -- 5 -- Preclinical studies: in vitro and animal research on the anti-breast activities of vinca alkaloids and its derivatives -- 6 -- Breast cancer clinical trials: the role of vinca alkaloids and derivatives -- 7 -- Commercial vinca alkaloids: pharmacokinetics, toxicity/adverse reactions and interactions
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| 505 |
8 |
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|a 7.1 -- Pharmacokinetics
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| 650 |
|
0 |
|a Antineoplastic agents
|x Development.
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| 650 |
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0 |
|a Breast
|x Cancer
|x Chemotherapy.
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| 650 |
|
0 |
|a Natural products.
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| 650 |
|
6 |
|a Sein
|0 (CaQQLa)201-0071080
|x Cancer
|0 (CaQQLa)201-0071080
|x Chimioth�erapie.
|0 (CaQQLa)201-0379519
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| 650 |
|
6 |
|a Produits naturels.
|0 (CaQQLa)201-0030192
|
| 650 |
|
7 |
|a Antineoplastic agents
|x Development
|2 fast
|0 (OCoLC)fst00810599
|
| 650 |
|
7 |
|a Breast
|x Cancer
|x Chemotherapy
|2 fast
|0 (OCoLC)fst00838266
|
| 650 |
|
7 |
|a Natural products
|2 fast
|0 (OCoLC)fst01034390
|
| 700 |
1 |
|
|a Brahmachari, Goutam,
|e editor.
|
| 776 |
0 |
8 |
|i Print version:
|z 9780128212776
|
| 856 |
4 |
0 |
|u https://sciencedirect.uam.elogim.com/science/book/9780128212776
|z Texto completo
|
